Peptide Protocols: Volume One

by William A. Seeds

This first-in-a-series handbook for physicians introduces the cellular biology behind peptides. Written by William A. Seeds, MD, the foremost authority on why and how to use peptides to delay cellular senescence, reduce inflammation throughout the body and the brain, and ultimately prevent disease and the effects of aging, Peptide Protocols offers physicians a foundational understanding of the brain and body through the lens of cellular functioning and how peptides can create better outcomes for all of their patients.Supported by extensive peer review studies, the protocols offered here offer insight and practical knowledge on how to support patients before, during and after treatment. This ground-breaking approach to disease prevention will change lives.

Genres: Nonfiction, Health

148 pages, Kindle Edition

First published January 1, 2020

Reviews

[Signe · Rating 3 out of 5]

It's a good primer, but the science has surpassed the basic info in this book already. I'm looking for more in-depth protocols and explanations of specific peptide uses; this book is a great start to the literature, but it's quite thin.

[Justin Evenson · Rating 5 out of 5]

As someone who has spent over a decade studying and personally experimenting with performance-enhancing compounds, from anabolic hormones to peptides and various pharmaceuticals, I eventually reached a point where I wanted to shift my focus from performance optimization to long-term health and repair. Over the last year, I’ve dedicated my research to peptide therapy, exploring its potential to support cardiovascular and renal function and overall systemic recovery. After countless studies, forums, and anecdotal reports, I finally came across this book, the first resource that brought everything together in a structured, evidence-based, and clinically grounded way.

Dr. Seeds takes an evidence-based, outcome-driven approach that sets him apart from most voices in this space. He isn’t speculating or theorizing, he’s actually applying these compounds in real clinical practice and documenting cases where peptides have helped patients recover from degenerative, inflammatory, and metabolic conditions that traditional medicine often only manages. Reading these examples adds legitimacy to what many of us in the peptide community have long observed: targeted cellular signaling can restore function, not just relieve symptoms.

He presents peptides as precision tools for biological repair, not performance enhancers or shortcuts. His explanations link peptide signaling to mitochondrial health, inflammation control, and tissue regeneration, all backed by clear mechanistic insight and conservative dosing guidelines. Each protocol feels methodical yet practical, making it useful to both clinicians and advanced researchers.

What I value most is his systems-biology perspective, addressing the upstream dysfunctions that drive disease rather than simply mitigating their downstream effects. That integrative philosophy reflects a deeper understanding of how the body heals when supported with the right biochemical environment.

It’s worth noting that this book was written roughly five years ago, and since then, new research and clinical data have expanded upon several of the protocols and applications he outlines. The peptide field has progressed rapidly, introducing newer, more innovative combinations and broader therapeutic potential.

If there’s one limitation, it’s that the book stays highly clinical and doesn’t incorporate much of the growing data emerging from the global underground research community. But in a world flooded with Reddit anecdotes and social media “experts,” that restraint gives it lasting credibility.

[Allison Thiessens · Rating 5 out of 5]

Highly recommend for anyone with interest in peptides

Loved how in-depth and technical he was in explaining cells and the process in which each peptide helps. Disappointed the book ended. I need more!

[Tony Wood · Rating 5 out of 5]

clear review

So much conflicting information floating around about peptides. This is a very well organized, detailed and clear answer to several questions I had about peptides in clinical settings.

[James · Rating 5 out of 5]

Interesting as hell. A little more science based than what I was expecting. But still intriguing and opens you up to alternative “medicines” to fix the root issue as opposed to only dealing with symptoms. World of peptides is fascinating to me.

[Stan · Rating 5 out of 5]

Wow! What a great book. It explains the technical sides of what peptides are and how the effect the body and how they function. It maybe a bit technical for some people but Dr Seeds is the master of peptides. Can wait for the next book! Thanks for all the information.

[Melvin Vera · Rating 5 out of 5]

A must read

This book give you relevant information, including properties of peptides, uses, and medical data to better understand protocols. Love it !

[Cherise Wolas · Rating 3 out of 5]

A little simplistic but a good start.