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Lives of Weeds: Opportunism, Resistance, Folly

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Lives of Weeds explores the tangled history of weeds and their relationship to humans. Through eight interwoven stories, John Cardina offers a fresh perspective on how these tenacious plants came about, why they are both inevitable and essential, and how their ecological success is ensured by determined efforts to eradicate them. Linking botany, history, ecology, and evolutionary biology to the social dimensions of humanity's ancient struggle with feral flora, Cardina shows how weeds have shaped--and are shaped by--the way we live in the natural world.

Weeds and attempts to control them drove nomads toward settled communities, encouraged social stratification, caused environmental disruptions, and have motivated the development of GMO crops. They have snared us in social inequality and economic instability, infested social norms of suburbia, caused rage in the American heartland, and played a part in perpetuating pesticide use worldwide. Lives of Weeds reveals how the technologies directed against weeds underlie ethical questions about agriculture and the environment, and leaves readers with a deeper understanding of how the weeds around us are entangled in our daily choices.

296 pages, Paperback

First published September 1, 2021

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John Cardina

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Displaying 1 - 18 of 18 reviews
Profile Image for Stanley (Stan) Enya.
98 reviews
June 21, 2021
Thanks to NetGalley and Cornell University Press for the ARC in exchange for an honest review

A truly fascinating read. The title caught my attention and I thought I’d give it a go. It definitely didn’t disappoint: lots of opportunism, resistance and folly. It’s probably easy to end up writing a terribly boring dud on a topic like this, especially if you’re writing for a general audience, but the author managed to keep me fully engaged throughout.

Lives of Weeds does a really good job at tackling a very big topic. Written by a self-described ‘weed guy’, the book explores different scientific aspects of weeds (e.g. genetics, ecology) as well as lots of cultural ones (e.g. history, what even is a ‘weed’?). I think the author did a really good job on both fronts, even if the scientific parts are predictably stronger due to his background.

Due to the nature and history of weeds, lots of the species the author discusses will be familiar to readers in Europe (my case), Africa and Asia, even though the author is predominantly writing from an American perspective. (I don’t think this is a conscious choice, and I wouldn’t fault the book if it only dealt with American species I didn’t recognise, but it means that it will probably resonate with people in many different countries and continents.)

Some of the key concepts, like ‘agrestal selection’, were things I’d never considered before. It’s really opened my eyes to a lot of more unknown natural processes, and it’s kinda crazy to think of that type of evolution happening so quickly right before our eyes. That fricked me up a little bit, I won’t lie.

It doesn’t require loads of specialist knowledge at all, but it does suppose a high-school(ish) level of genetics for some of the more scientific sections on how weeds evolve. I had to check a few specific points to really understand what was going on, but it wouldn’t have been the end of the world if I’d just gone over those sections without understanding them perfectly.

I know veeeeeeery little about botany (although I feel like I know a lot more now!), so I’m in no position to have opinions on the more subjective parts of the book and I was happy to take them at face value. I imagine specialists might have a different reaction to some of the claims.

It’s also really well written, which is something I never take for granted in books like this. I often found myself highlighting bits that were quite pithy (‘Few things advance the ecological success of a weed beyond an organized attempt to exterminate it’). The author is funny and sarcastic at times (like when he refers to a long list of environmentally destructive practices as ‘hallmarks of progress’), and his personality does shine through the writing a lot without getting in the way of the story too much.

One thing I wasn’t crazy about is the way the author is kind of vague on genetic engineering as a technology. He does make an understated comment about anti-GMO sentiment not being backed by science and the obviously positive applications of genetic engineering – you know, like some Covid-19 vaccines and insulin (my examples) – but he seems a bit too evasive, like he’s just not interested in opening that can of (genetically modified) worms. I understand not wanting to go into it if it’s gonna alienate half your audience, and I assume a significant portion of the intended audience is vehemently ‘anti-GMO’. He seems to walk on eggshells when it comes to tricky topics, often in a way that manages to avoid upsetting either camp, which ended up frustrating me a little. To be fair, I have no reason to think that the author is ‘against’ genetic engineering as a technology, but in being vague and evasive on the topic, I think it’s easy to read it as such (especially if that’s already your position going into it) instead of him simply having understandable and valid complaints and concerns about the way genetic engineering is carried out for profit by huge companies in a capitalist system, often at the expense of people and planet, which is REALLY not the same thing. I thought it was a bit of a cop-out. But it’s a minor issue, and it’s more about the way some people might interpret it than what’s actually written there – it just seems shifty to me.

Anyway, definitely one of the best things I’ve read this year, and I totally recommend it to anyone who likes reading non-fiction about the natural world, especially more unfamiliar topics that turn out to be unexpectedly relevant.
Profile Image for Mandy.
3,623 reviews333 followers
October 10, 2021
An important and timely book, this exploration of weeds covers every aspect of them – ecology, agriculture, science, conservation, medicine and so much more – and is a meticulously researched and comprehensive study of the plants that are usually considered worthless and something to be erased but which in fact have a whole other existence that I was not aware of. In fact I’m astonished by how much I didn’t know before I read this wonderful book. Mind you, I did feel as though I were drowning in weeds and their science at times but that was a small price to pay. If nothing else I came away with a deep respect for weeds and will never look upon them in quite the same way again.
274 reviews1 follower
October 12, 2022
In case you think I mistakenly gave five stars to John Cardina's Lives of Weeds: Opportunism, Resistance, Folly -- I did not. Cardina has written a captivating book on a select number of weeds that have become more than a nuisance to many farmers and gardeners across the globe. With thick slices of history and botany that are each well-seasoned with a wry sense of humor, Cardina lays out how civilization has been complicit in creating our weedy problems over the centuries. The weeds themselves present a sizeable issue, but that has been compounded by use of chemical agents that have promised much, but delivered little except adding a layer of toxicity to a problem that only continues to grow larger and more complex. Cardina cautions us to carefully consider future alternatives and presents possible scenarios for each choice. From the introduction onward, I chuckled - and at times laughed out loud -- as I learned many lessons from history and science as well as the consequences of mankind's actions and impacts across the years. Lives of Weeds is a historical and scientific book -- and also a cautionary tale.
Profile Image for Hugo Veríssimo.
36 reviews
July 20, 2025
This book has really interesting insights about how weeds interact with humans and how persistent they and us can be in this never ending battle on who occupies the place in the sunshine. A battle that might be briefly won by us, but a war that is already lost. There’s just to much evolutionary wisdom in weeds that have been around for so long.
With this being said, I feel the author had a lot of moments when he was just repeating himself from previous chapters and sometimes I felt there was just too much details that weren’t really useful or relevant for the reader.
Profile Image for Amber.
156 reviews
August 13, 2025
Excellent information on 8 common weeds (bear in mind, the term "weed" can realistically be used for any plant you as an individual don't like or want on your property and can differ amongst peoples and cultures...) - perfect for us garden nerds! 🌿😎
Profile Image for Jennifer Anderson.
4 reviews1 follower
June 14, 2021
How does one write a jarring narrative about weeds? Ask John Cardina. Approaching his “Lives of Weeds”, I was not at all prepared for such an uncomfortable encounter (or anything else along the anxiety spectrum for that matter!). Pencil in hand, I readied myself for a primer on these gritty (sometimes prickly) challengers of crop resources. Not far into the first chapter, though, the pencil was down and I was completely absorbed in his holistic analysis integrating history, social and cultural norms, technological innovations, and his expertise: weed science.

Starting first with the common dandelion, the narrative is intriguing, pleasant, and almost laughable. From its earliest origins, Cardina traces its arrival to the New World--a time in which it graced dinner plates and medicine bags alike. In those days, lines of poetry extolled its cheerful presence and marveled at its floating ball of seeds. Early pioneers found enough utility in the plant (as it was not yet a weed) and cleared land to ensure its steady supply.

By the early 19th century, however, human fickleness determined that the grass was greener on English estates. Cardina credits Thomas Jefferson for creating the earliest notions of the suburban lawn that grew to symbolize prosperity (as, “only poor folk or sinners let dandelions bloom”). The ensuing pursuit of a flawless lawn required slaves and all manners of inventions to eradicate any yellow aberrations. But true to Newton’s Third Law, every (human) action inferred an equal and opposite (weed) reaction. Exhaustive attempts to manually pluck it from existence stimulated buds deeper on the root. Rakes devised to remove the flower before it seeded resulted in shorter stems, keeping the flower closer to the ground and out of the rake’s reach. More sophisticated mowers distributed its willowy seed sack evenly and at larger distances. Burning them brought only temporary satisfaction until a new growth of buds emerged. Humans upped the ante post-WWII with high dose applications of 2,4-D--a hormone originally intended to stimulate growth of plants. Encouraging early results combined with the period’s enthusiasm for capitalism ignited a multi-billion dollar herbicide industry. Cardina reports that Americans now spend over $900 million annually on lawn chemicals, a point to which he adds “a quick glance out the window in springtime shows how well that has worked out.”

Having established this concept of “agrestal selection”--the unexpected adaptations plants take at the response to human intervention--Cardina turns his focus on 7 additional species’ extraordinary evolution and the farmers they entangle. Although he provides detailed context to explain the current state of affairs, the read becomes sobering. Each example is merely a snapshot of a complex system still in motion. In this case, unfortunately, past performance is no predictor of future results, particularly as chemical innovations give way to genetic engineering, all while climate volatility threatens an already overextended and overexploited industry. And so it was with wide eyes that I absorbed the implications for the adaptive mechanisms weeds are undertaking such as seed dormancy (ability to delay seed germination to ensure its survival; in some weeds, this can be up to 40 years), plasticity (ability to adapt physically in response to surroundings), and allelopathy (ability to inhibit growth of adjacent plants through release of chemicals). Paired with herbicide resistance--the “everlasting” pigweed has outwitted numerous--and the ability for winddriven pollen and seeds to travel hundreds of miles, no farming operation is immune to these superweed mutations. But such is the course that industrial agriculture conglomerates are demanding.

Cardina rightly asks the question: is this what we really want?

It’d be a useless question if there weren’t other ways (and he points to examples that are working!).

While “voting with a fork” as he suggests is equally important, many of us don’t yet understand how to vote and why. If that is you, this book is a great place to start. To anyone interested in living sustainably, supporting farmers (particularly those making the transition to regenerative farming practices), or even questioning what all the climate fuss is about, I highly recommend “Lives of Weeds”. It’s an incredible work from a unique and sound perspective.

Thank you Dr. Cardina, Cornell University Press, and NetGalley for extending an Advanced Reader Copy of this book!
Profile Image for Linda Is on her way.
221 reviews1 follower
August 21, 2024
It's a bit too scientific for me. I mean in a way that I didn't really understand the stuff about the agricultural in depth things. I've never really learned much about that so it was a sort of introduction to this topic for me. Therefore it's not the book, I'm the problem. My attention drifted then and I missed some parts. I would've found it more interesting if it had been heavier on the botanical stuff, but that's personal preference. In most cases I share the authors opinion and I also liked the epilogue. I listened to the audiobook of this. I had to force myself a bit to keep going but I'm glad I read or rather listened to the book now. It's definitely a good book though, that's why I'm giving it four stars (even though for me personally it was a three star but the book doesn't deserve that).
1 review
April 10, 2022
Weeds are resilient. They are always ahead in the race in which the humans trying to eliminate them. Weeds are the results of activities of modern humans and are closely linked to modern farming practices. But the author covers the story from weeds' point of view. Weeds are antifragile. The grow stronger from every attempt to eliminate them. Their evolutionary success is profund and they are helped by shortsightedness of humans and their tendency to quickfix the problem rather than finding a lasting solution to weeds problem. An excellent book, written in such a way that you cover a journey through author's mind, and senses.
149 reviews2 followers
May 29, 2025
What is a weed? It will not shock anyone who pays attention to words that “it depends” and that the definition depends mostly on context, human experience and actions, and cultural meaning. This is really good science writing that explores a lot of topics by taking the reader through eight “pathways” of weediness. How do plants become weeds—literally?
146 reviews8 followers
July 3, 2022
This is a real gem. It's really valuable to put weeds in the centre of analysis and begin understanding their coevolution with us, and the speed at which evolution can take place under agrestal selection. Makes weeding feel much more profound.
339 reviews1 follower
April 27, 2024
Interesting approach - mainly looking at weeds from an agricultural point of view, focussing on weed control, via herbicides (eg 2,4D and glyphosate) and crops: cotton, peanuts and soybeans. Lots of info on GM crops’ and weeds’ herbicide resistance.
Profile Image for Emilio Socías.
59 reviews1 follower
December 8, 2025
who knew weed biology could be so interesting? It's been a couple of months since i started reading non-fiction books and it's been one hell of a ride. I've had luck so far, listening to amazing books by amazing authors. This is definitely one of my favorites so far. There are so many layers to one topic and i feel like John Cardina managed to show this in a superb way. Every chapter of this book centers around a different weed, its biology, its evolutionary history, its relationship with humans and the authors' experience dealing with it.
This book feels like a recounting of all our mistakes as a species. De manera general, seguimos buscando maneras de eficientizar procesos tomando atajos que terminan haciéndonos daño a nosotros mismos y a nuestro entorno. Es gracioso, de cierta manera, la forma en que el autor, como académico, señala la cantidad de estudios que ha hecho con respecto a cada especie de hierba y como los resultados para mitigar su presencia son muy similares: rota los cultivos, no abusen de los herbicidas, intenten implementar un sistema más diverso de plantaciones… A pesar de esto, llevarlo de recomendaciones a práctica resulta una tarea casi imposible, pues la mentalidad el siglo XXI está firmemente plantada en aumentar la producción sin importar los daños a los recursos naturales. Con cada pedazo nuevo de información que recibo quedo más convencido de que, para salvar el planeta, tenemos que hacer un cambio profundo a nivel cultural, restablecer nuestras prioridades como entes activos de la sociedad y comenzar a implementar nuevos hábitos de sostenibilidad alejados de un consumismo impulsivo. That being said, these things are easier said then done.
This book was an eye-opener in other ways as well. Through his discussion of scientific research in weed biology and the nature of these plants, John Cardina presents a compelling case for rethinking weeds as a concept—and for recognizing the limitations in how we understand them. Plants respond to their environments; it’s simply how nature operates. We can’t expect them to stop adapting and evolving just because it suits us. Instead of integrating ourselves into the natural order, we try to rewrite it. No wonder everything feels like a constant struggle.
There are so many good things i can say about this book and the ways it impacted my life. I would definitively recommend it to anyone looking for a book on science, weeds, agrestal selection and environmental ecology. 20/10
53 reviews
July 30, 2022
Interesting. I wanted to know what made a weed a weed.....and I think this book is pretty clear in the answer. Well written, easy to read- should appeal to anyone with an interest in how humans and agriculture affect the world.
Profile Image for Christian Moore-Anderson.
Author 2 books9 followers
March 8, 2022
This was a really nicely written book. As a biology teacher I also found it very insightful and useful for discussions in my lessons. Highly recommended.
Profile Image for Melissa.
20 reviews1 follower
April 1, 2023
Important information how the progress of women in developing countries is intimately intertwined with weeds. Note to self to refer back to this in the future.
Profile Image for Noanodium.
50 reviews
December 30, 2025
The 'weed guy' will haunt me in my nightmares.

Edit: Originally I skipped 2 or 3 chapters since I didn't think they were relevant to my research but after reading the chapter about ragweeds I am forced to change my rating from 3 stars to solid 4. Weed guy is weird and he makes me uncomfortable but I like how he thinks sometimes.
Profile Image for Kait Leeming.
271 reviews1 follower
January 1, 2024
This book is the work of weed-scientist John cardina in which he traces the history of our battle against weeds in home and agriculture, choosing 10 interesting varieties to focus on. What is a weed? Why are some weeds more fashionable than others? How has our relationship with plants deemed weeds changed? How have the weeds changed to adapt to our methods of cultivation and control? This fascinating little read is accessible and relatable and may change your perspective on the humble dandelion and other successful weeds.
Displaying 1 - 18 of 18 reviews

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