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Healthy Heart, Healthy Brain: The Personalized Path to Protect Your Memory, Prevent Heart Attacks and Strokes, and Avoid Chronic Illness

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Boost your cardiovascular health, optimize your mental strength, and prevent and reverse arterial disease with this personalized plan from the founders of the renowned Heart Attack & Stroke Prevention Center –– “you’ll want to read every page” (Amen).
 
Did you know that every forty seconds, someone in the US suffers a heart attack or stroke, and every sixty-five seconds someone develops dementia? The culprit is cardiovascular disease—and rates are soaring in younger, seemingly healthy people. Busting every myth we have about cardiovascular health, including that women are less likely to suffer from heart attacks and strokes, world-renowned cardiovascular specialists Bradley Bale, MD, and Amy Doneen, DNP, have pioneered a lifesaving method to prevent these devastating events—and reverse the disease that causes them.
 
The BaleDoneen Method transcends the medical silos of cardiology, neurology, endocrinology, and others with a holistic approach designed to protect and optimize the health of the heart, brain, and other vital organs, as well as the blood vessels that supply them. With laser-sharp focus, Bale and Doneen provide the latest research on how your oral health is contributing to the decline of your heart. Captivating and revolutionary,  Healthy Heart, Healthy Brain  is a unique and comprehensive program to prevent chronic diseases and memory loss in people of all ages regardless of their body type, medical history, or genes. Offering a roadmap to lifelong arterial wellness, it
Healthy Heart, Healthy Brain  will equip you with the knowledge you need to approach your healthcare as an empowered and informed patient.

464 pages, Hardcover

Published March 15, 2022

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Displaying 1 - 23 of 23 reviews
Profile Image for Candace.
950 reviews
May 20, 2022
Quite honestly, I found this book interesting and helpful, but I got lost a few times in the abbreviations for the diseases and tests. I wish the authors would have spelled out the abbreviations a few times to remind me what they stood for. I did find the research extensive and the latest findings, including some 2022 studies. At the back of the book is an Appendix: Optimal Goals and Health Metrics Chart. I found the Appendix helpful and easier to comprehend because it gave the test names and its abbreviation, plus the purpose for the test and the optimal range for a healthy, happy heart.
Profile Image for Karlie.
537 reviews11 followers
March 22, 2022
I loved Beat The Heart Attack gene. This is sort of an updated and a bit more simplified version of it which I appreciated. I do feel there were way too many anecdotal stories in it and a lot of repetition. (From that point I would have rated it lower but it’s overall content deserve a high mark) I did appreciate refreshing what I got from the first book and adding to it even more with the brain aspect too. I still will recommend the first one more although this one may be better geared for the lay person. As a dentist, I really appreciated the continued insights on the oral health and systemic health correlation. The first one showed helped me learn more about risk factors and genetic factors I didn’t know I had so I can be more aware. This one reminded me of things I had forgotten about from the first and helped me realize some of the things I still personally need to work on. I still wish I had better resources for a Mediterranean diet plan. I highly recommend the Bale and Doneen way of looking at your health and appreciate all they have done publicizing it.
Profile Image for Robin Loves Reading.
3,021 reviews453 followers
March 30, 2022
This is an excellent book about how a team of medical professionals work to perfect the Bale/Doneen method to help prevent heart attacks and strokes, while also using their knowledge to improve memory and other relevant medical issues.

I loved this book and enjoyed making the YouTube video review for this title: https://youtu.be/fZpxdDp2I18
Profile Image for Cheryl A..
13.6k reviews491 followers
April 24, 2026
TLDR: Read the book! If you have risk factors and don't feel like your provider is taking your concerns seriously, buy the book! There's so much I haven't covered in my long review below.
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Hmm. Started. A good primary care provider will look at the whole patient, collecting risk factors and numbers and etc. across 'specialties.' One only sees specialists if recommended by primary, no? Even though I have insufficient Marketplace insurance (not quite old enough for Medicare) I feel like my provider looks at my concerns from a bunch of different angles and also that she adds them up in context with one another.

I'm barely into it, but I suspect that I may not be able to get all the tests Bale advises, unless I self-pay for at least some of them. I also suspect that the advice will correspond to what we all know, such as exercise, don't smoke, get enough sleep.... But we'll see.

Quite a few book-darts from the very beginning seem to set the tone and to set up the agenda:

The new medical specialty of arteriology is... designed to transcend the traditional medical silos that result in incomplete, fragmented care for people with blood vessel disorders. For example, patients who suffer strokes are typically managed by neurologists, while those who have heart attacks are treated by cardiologists - even though almost all these events stem from the same cause: plaque that has been growing silently inside an artery wall becomes so inflamed that it ruptures explosively, like a volcano spewing molten lava. In an attempt to heal the breach, the blood vessel forms a clot. If the clot travels to the brain and blocks one of its arteries, the result is a stroke. If the clot obstructs a coronary artery, a heart attack can occur."

"Large studies have shown that one of the simplest - and most effective keys to a longer healthier life is to combine regular dental checkups with excellent self-care."

"It is now widely recognized that the majority of heart attacks and strokes are silent. Although these events don't cause any obvious symptoms when they occur, they cause hidden damage to tiny arteries ... that over time can lead to many diseases of aging."

"Our method extinguishes the chronic inflammation that contributes to these conditions, thus helping to prevent many of the devastating disorders that result in people outliving their health. New research reveals that most people live the final 13 years of their life in an unhealthy state."

Ok done.
Lots more book darts. Basically, the idea is that our body is a system and everything has to be able to work together. And each of us is unique. The general advice, the universally proscribed meds, examinations that don't check everything including dna, are important but absolutely not sufficient.

So, the bottom line is, if you have any risk factors at all, get as many of these tests as you can afford (and many are covered if they're actually ordered, and many are cheap), do all the standard Mediterranean Diet, exercise, sleep, etc, advice, and then take the prescriptions & supplements that are Customized by your Primary Care Provider or your cardiologist (or whatever other specialist you might find yourself getting care from) for you, yourself.

Family history is one of the biggest risk factors.
Other health issues like ED, gout, sleep apnea, prediabetes, etc. etc., count. Even Frank's sign, a fold in your earlobe, should be noted. Don't panic if you have some risk factors, but note them for the big picture.

Bleeding gums/ periodontal disease is a big deal - get your teeth cleaned twice a year & talk to your dentist about what he sees & advises. If he doesn't understand or won't make time, get a new one.

Examples of tests that are more nuanced than the standard are ApoB and Lp(a) instead of just cholesterol. Speaking of, taking a statin can do good things even for people with normal cholesterol levels as it is anti-inflammatory (but see the book for clarification). But women, do not take Lipitor, try rosuvastatin (Crestor). There are other people who will not benefit from statins and should not be on them.

Don't accept 'oh your numbers look good' from your primary. Get your numbers, know what they mean, compare them to last year's work-up. High blood pressure, for example, needs to be 120/80 or less, but not made artificially too low, and is nuanced. A little higher than that is not 'good enough' if you have any other risk factors.

Apples are good for your gut biome.

An extra good movement is dance. Listening to music, learning new steps & moves, experiencing joy, all give boosts that just plain walking doesn't. Even better, grab a friend or partner and teach them your new moves. Try videos on youtube if you're too introverted to go to Zumba or the classes at the senior center.

Strength training twice a week is good, too. I used to do this and would like to again. I'll have to figure out how!

The book advises intermittent fasting 16/8. I'm not 100% convinced but I can do 12/12 if that would count. Worth a try.

Mindful meditation (or prayer) can reduce stress, fight inflammation, combat depression, and even keep the brain sharp. Does 'counting sheep' count?

Find laughter in laughter yoga, silly videos, a joke-a-day calendar, or a comedy club might boost your level of optimism. Even if it doesn't, it's still good for you.

Another important test is MyPGt. Helps match your genetic make-up to the drugs you're taking and many other medications, for the Custom aspect mentioned above.

High blood pressure is often triggered by insulin resistance, which causes 70% of heart attacks.

(There's a big long chart in the back for all the tests & their goals.)
Profile Image for Julie.
726 reviews2 followers
January 25, 2024
I listened to the audio version of this book and found it fascinating and informative. If you or a loved one has high blood pressure or high cholesterol or dementia or diabetes or are at risk for any of the above, read this book. There is a quiz at the beginning to tell you where you fall as far as risks for arterial diseases. The doctors suggest several different tests not always thought of by primary care physicians.
Profile Image for John  .
167 reviews
September 4, 2022
Leans a little heavily into the "more tests are more good" thing. Seems like the kind of medical textbook that could convince Hercules himself that he's on death's door.
Profile Image for Francine Abel.
108 reviews11 followers
February 5, 2023
I enjoyed the part how you can influence your health by eating a good diet, exercise tc, but as for all the tests I should be getting to know my risks, I know that this is not an option. These tests are not offer in a preventive manner here in Canada.
Profile Image for ie.
3 reviews
January 16, 2026
This is a feedback about the book, and also about patience, endurance, and the human capacity to keep reading while repeatedly wondering why. I will recommend the book later - not immediately, but soon enough, if you stay with me.

Let’s start with the style. The writing is somewhere between a medical lecture and a very long hallway where the exit sign keeps moving farther away. Important things are said, then said again, then gently rearranged and said once more, just to be safe. Several times I was close to marking the book as DNF, but recommendations elsewhere insisted it “must be finished,” which made it feel less like reading and more like a cardiovascular stress test.

Here’s the paradox. The ideas, facts, and recommendations are actually strong. Some are genuinely interesting, some practical, and some worth highlighting or revisiting later. The author clearly did enormous work - research, synthesis, and care are all present. The problem is not what is said, but how long it takes to say it. If information were calories, this book would be very healthy and very hard to chew.

To make an analogy: I would like to recommend this book, and I am now recommending it. I previously mentioned that I would recommend it later, and now that later has arrived. As mentioned earlier, this is a recommendation, based on reading the book, not on other recommendations. I know how to read. I learned how to read. I have evidence. Others may also read, but sometimes they mainly type words. Please stay with me until sentence twenty-five, where the recommendation becomes emotionally clear.

The book is also very America-centric. The healthcare assumptions, lifestyle framing, and cultural references make it feel written primarily for an American audience. In that sense, it will likely resonate most with readers who enjoy clear rules, strong personal responsibility narratives, and familiar political-cultural undertones. Some readers may even feel it aligns comfortably with a Trump-era worldview - not aggressively, but unmistakably.

Final verdict: this is a good book trapped inside a difficult book. If you have patience, discipline, and a high tolerance for repetition, you’ll be rewarded with solid insights. If you don’t, you may still finish it - but only because someone on the internet told you that you should.
Profile Image for Healthypedia.
218 reviews12 followers
November 7, 2023
Learn how to prevent heart and brain disease through a holistic approach to cardiovascular health with ‘Healthy Heart, Healthy Brain.’

Were you aware that in the United States, a heart attack or stroke occurs every forty seconds, and dementia develops in someone every sixty-five seconds?

In their groundbreaking book ‘Healthy Heart, Healthy Brain,’ internationally acclaimed cardiovascular experts Dr. Bradley Bale and Dr. Amy Doneen introduce an innovative approach to prevent these catastrophic occurrences and even reverse the underlying condition responsible for them.

In this review, we will take a closer look at the book and learn about how to prevent heart and brain diseases before they are even evident.


About the authors

Dr. Bradley Bale and Dr. Amy Doneen are renowned international leaders in the field of preventive medicine, specialising in heart attack, stroke, type 2 diabetes, dementia, and chronic disease prevention.

They are the co-founders of the BaleDoneen Method, established in 1999, which has been proven effective in identifying, stabilising, and reversing arterial disease through peer-reviewed studies.

Both doctors hold academic appointments at prominent institutions and have contributed significantly to the field of preventive medicine. Dr. Doneen operates the Heart Attack & Stroke Prevention Center in Spokane, Washington, where she provides patient care and trains healthcare providers in the BaleDoneen Method.


What is the book about?

“Superior doctors prevent the disease. Mediocre doctors treat the disease before it is evident. Inferior doctors treat the full-blown disease.”

The book ‘Healthy Heart, Healthy Brain’ aims to enable readers to boost their cardiovascular health and prevent arterial disease by following a personalised plan from Dr. Bradley Bale and Dr. Amy Doneen, the founders of the renowned Heart Attack & Stroke Prevention Center.

The BaleDoneen Method takes a holistic approach that goes beyond individual medical specialities like cardiology, neurology, and endocrinology. It aims to optimise the health of the heart, brain, and other vital organs, as well as the blood vessels that supply them.

‘Healthy Heart, Healthy Brain’ presents a comprehensive program designed to prevent chronic diseases and memory loss in people of all ages, regardless of their body type, medical history, or genes. It includes precision medical methods to prevent ageing-related diseases, information on the best and worst supplements and foods for heart health, ten lifestyle moves to reduce dementia risk, insights into genes that elevate cardiovascular risk, and the top ten heart attack prevention tips for women.

With its focus on reclaiming health and introducing simple screening tests and diagnostics, ‘Healthy Heart, Healthy Brain’ transforms the concept of preventative medicine and holistic health. Drs. Bale and Doneen’s approach eliminates the need to visit different specialists for various body parts, making it a crucial read for those seeking to prioritise their health and longevity.


Key takeaways from ‘Healthy Heart, Healthy Brain’

1. Dental and cardiovascular health are closely interconnected

The book emphasises the link between cardiovascular and dental health. Periodontitis, also known as gum disease, makes you more susceptible to various chronic conditions including heart and brain ones.

In fact, people with periodontitis are 2.5 times more likely to suffer heart attacks and 70% more likely to develop Alzheimer’s than those with healthy gums.

It is advised to partner with your dental provider and establish objectives to elevate your oral health to a higher standard; request your dental provider to screen for periodontal and endodontic issues and assess you for high-risk oral bacteria; maintain regular brushing and flossing routines as they contribute to disinfecting your entire mouth; and schedule dental cleanings at least twice a year or as recommended by your dental provider.

2. Intermittent fasting has a plethora of cardiovascular benefits

Intermittent fasting is usually taken as a method of losing weight. However, it offers a multitude of cardiovascular benefits, as evidenced by new and recent studies. Adopting this eating regimen can help prevent the development of arterial plaque by reducing cholesterol trapping, lowering endothelial inflammation, and decreasing levels of harmful particles like small, dense LDL and ApoB. Moreover, individuals practising intermittent fasting can experience significant improvements in their arterial wellness, including reduced risk for blood clots.

The book provides an example of a clinical trial conducted in 2021 that further revealed that intermittent fasting leads to decreased body fat, oxidative stress, and inflammatory markers, while also improving blood vessel function, food metabolism, and gut health.

3. Mindful practices enhance cardiovascular health through stress alleviation

Chronic stress can significantly increase the risk of heart attacks and strokes. The activation of the amygdala, a brain area involved in stress, can lead to arterial inflammation and further contribute to cardiovascular risks.

‘Healthy Heart, Healthy Brain’ suggests incorporating mindful meditation and prayer into daily life can effectively reduce stress and anxiety, promoting better arterial wellness. Mindfulness has shown remarkable health benefits, including preserving brain sharpness, reducing inflammation and stress, alleviating chest pain and stress in heart patients, lowering blood pressure, and combating or preventing depression. By adopting mindful practices, individuals can not only enhance their psychological well-being but also protect their cardiovascular health, making it a vital tool for overall wellness.

Strengths and weaknesses, according to readers’ reviews

Strengths:
• Extensive research and up-to-date findings, including studies from 2022, provide credible and reliable information.
• Provides actionable advice on preventing cardiovascular disease alongside theoretical information.
• Empowers readers to take charge of their health with accurate information, making it suitable for individuals seeking to improve their lifestyle and well-being.

Weaknesses:
• Some readers feel overwhelmed by the abundance of recommendations for medical tests, which they perceive as intrusive and potentially leading to self-diagnosing non-existent health issues.


Best quotes from ‘Healthy Heart, Healthy Brain’

“Our patients are often shocked to learn that most medical providers still screen patients for arterial disease in the same way they did in the 1990s, when Bill Clinton was president, the macarena was the hottest dance craze... In that era, a then-new screening tool called Framingham Risk Score (FRS) was introduced to help providers identify which patients might be at increased risk for heart attacks and strokes, so they could receive preventive care to protect their arterial health.”

“The researchers report that patients with one copy of the gene responsible for elevated Lp(a) levels are 58 percent more likely to develop coronary heart disease (CHD) while taking a statin for prevention than those without the gene, while risk for CHD is more than doubled in statin users with two copies of the Lp(a) gene!”

“For decades, LDL cholesterol has been vilified as public enemy number one by the medical profession. Yet none of the hundreds of cholesterol studies performed to date has ever shown that LDL causes heart attacks.”



Final takeaway

‘Healthy Heart, Healthy Brain’ by Dr. Bradley Bale and Dr. Amy Doneen is a groundbreaking book that offers a comprehensive and innovative approach to prevent heart attacks, strokes, and dementia, while optimising overall cardiovascular health.

This book is highly recommended for individuals seeking to proactively improve their lifestyle and protect their health. By delving into the topics covered in ‘Healthy Heart, Healthy Brain,’ readers can gain valuable insights and actionable steps to lead a heart-healthy life.
Profile Image for Tina Leibel.
11 reviews1 follower
July 9, 2022
As a Canadian RN that works in cardiac critical care units .. I absolutely recommend this book. We must look out for our own health to have a good quality of life as we age. Not sure all these lab and diagnostic tests in this book are available in Canada though. I will have to look into that. This book is very informative and if we as individuals know why we are taking certain drugs and benefits of healthy diet and a regular exercise regimen I believe we are much more inclined to follow through with recommendations. We must empower ourself with good sources of accurate information to live our healthiest lifestyle. I thank Dr Bale and Dr Doneen for writing this book, it is good to see medical professionals promoting prevention.
409 reviews1 follower
February 7, 2024
Really like the book, REALLY hate the comics. It’s as if one of the author’s had an unemployable cousin and they had to find a purpose for him. They have done themselves a disservice. First, it’s a serious topic and my adding these silly images, they make light of a topic that is not humorous. Second, the drawings are so far removed from what the ideological image they are supposed to depict, it’s just silly.
Profile Image for Kathleen Scales.
9 reviews1 follower
August 20, 2025
This is an important topic, and I appreciate that the authors stress a personalized approach. At times the book feels overwhelming and the science is technical, but the repetition of key factors helps. I took notes, and I plan to use the information in this book to support ongoing consideration and conversations with my healthcare providers and family members.
Profile Image for Whitney.
457 reviews
Read
June 29, 2022
A lot of information. Not all of it is new if you've read Weil, Hyman, etc recently. Still a good refresher and the first time I've ever seen a great emphasis on dental care in relation to systemic health .
Profile Image for David Molina.
81 reviews
August 15, 2023
Gained a lot of knowledge about the link between many conditions and life style decisions and your heart health. It was well written but not a light read. I was most surprised by the link between dental health and heart health.
Profile Image for Debbie.
1,032 reviews
March 30, 2022
Gives the latest research -- focusing on heart health. Life saving info!
Profile Image for Helen.
845 reviews11 followers
June 16, 2022
Lots of good advice and some interesting symptoms to watch for.
Profile Image for Ian McGaffey.
605 reviews2 followers
December 22, 2022
This was a good read of a little disheartening at times. Definitely full of good information and some options to make changes to control heart health.
Profile Image for John Jennings.
201 reviews5 followers
December 30, 2022
The reason for the 5-star review is because the book answers why "unhealthy people" don't suffer from health issues and why "healthy people" do.
17 reviews
July 22, 2023
EXCELLENT READ

They explain everything so that a lay person can understand. Yet, much of the information is science-based, and thus valuable even to a physician internist.
117 reviews
November 17, 2024
Read this or their other book Beat the Heart Attack Gene. No reason to read both.
Profile Image for Kim.
192 reviews
May 31, 2025
The information was helpful especially if you aging and find yourself with some of these issues or predisposed genetics.
5 reviews
December 9, 2025
Content is 5-stars. I am healthy and want to stay that way, but you do have to wade through a lot of content about very sick people trying to turn their lives around.
Displaying 1 - 23 of 23 reviews