The Microdosing Guidebook: A Step-by-Step Manual to Improve Your Physical and Mental Health through Psychedelic Medicine

by C.J. Spotswood

Learn about the history, scientific research, and wellness benefits of microdosing psychedelic medicine like psilocybin, LSD, MDMA (ecstasy), and more with this unique combination self-help book and guided journal.

Microdosing, or taking between 1/10th and 1/20th of a standard dose of a psychedelic, is a growing method to boost performance, ease chronic pain, and help with conditions such as anxiety and depression. Unlike a full psychedelic trip, microdosing allows you to maintain clarity while enhancing your day-to-day experience. Part handbook, part journal, The Microdosing Guidebook is your trusted resource for safely exploring psychedelic therapy. Inside, you'll

The most up-to-date research on psychedelicsA complete history of psychedelic medicineTips to find your ideal microdose based on body chemistryPages to track your experiences and progressAnd more!
Whether you're experienced or new to psychedelic wellness, The Microdosing Guidebook is a valuable guide to start your healing journey.

Genres: Self Help, Science, Psychology

288 pages, Paperback

Published July 8, 2022

Reviews

[Col Sullivan · Rating 5 out of 5]

The Microdosing Guidebook:
Day 1: dose
Day 2: off//reflect
Day 3: off/reset & reflect
Day 4: dose/restart cycle

For creativity: dose less
For depression: dose more

Effects dependent on body weight & metabolism

Journal:
- What was intention?
- Mental health/mood/emotions
- Senses
- Concentration
- Social
- Introspection
- Creativity
- Physical
- Evaluation

Psychedelic substances have an association with anti-inflammatory effects.

- “Microdoses allow lower the imaginary barrier between our conscious and unconscious mind, allowing information to stream with ease.”


[DIFFERENCES NOT KNOWN;WELL UNDERSTOOD]

LSD:
- “Cleaner”
- Better suited for self discovery & cognitive improvements
- Pharmacological feel (made in lab)

Psilocybin:
- Better for physical improvements
- Better for mental health improvements, or feeling closer to others
- Natural (not made in lab)

STUDY (338 participants)

Depression:
- (227) 72% found improvement
- (15) 5% worsened
- (74) 23% no effect
Anxiety:
- (177) 57% found improvement
- (41) 23% worsened
- (95) 30% no effect
Memory:
- (122) 39% found improvement
- (46) 15% worsened
- (146) 47% no effect
Focus:
- (184) 59% found improvement
- (46) 15% worsened
- (82) 26% no effect
Sociability:
- (209) 67% found improvement
- (35) 11% worsened
- (70) 22% no effect

Side effects:
- Insomnia
- Nausea
- Anxiety

The Stamets Stack
1. 1-10 mg of psilocybin (microdose)
2. 500-1000 mg of lions main (memory + cognition)
3. 100-200 mg of niacin/B3 (anxiety + circulation of 1 & 2

Stamets Method ≈ 5 days on, 2 days off

Antidepressant medication side effects:
- headaches
- Dizziness
- Nausea
- Anxiety/restlessness
- Sleep disturbances
- Dry mouth
- Simone’s sex drive
- Inability to orgasm

Psychedelics - change the way one thinks
Antidepressants - change emotional responses

2nd half of Book is a journal/note section for readers

[Matt Newman · Rating 5 out of 5]

I've chosen to give this book 5* because it has brought so much information together into one book. Most of the other books on this subject are a lot less comprehensive. You could probably find most of the info on the internet, but only if you knew what to look for. For all the articles I had read online I hadn't come across many that mention the possible interactions with other medications that his book details or some of the other possible side effects that were mentioned.

I'm not on a psychedelic journey, but if I ever did choose to go down that path I feel well prepared and informed about what to expect. I recommend this book to anyone who is thinking about going down that path or has maybe just started out.

[Blanka Pawlak · Rating 5 out of 5]

A science-based manual for exploring microdosing safely and effectively.

• Clear, structured 6-week workbook format
• Combines science, psychology, and practical tools
• Covers dosage, safety, and tracking in detail
• Written by a psychiatric nurse with clinical insight
• Perfect for beginners and experienced users alike

A balanced, informative, and empowering guide to understanding microdosing in a responsible, mindful way.

[Laura · Rating 1 out of 5]

There are better books available on this subject. Poor writing and editing severely undermine what this book is trying to do. Spotswood’s reliability takes hit after hit because of spelling errors and sentence redundancy that could’ve been caught by a simple copy edit.