This volume provides an account of the critical contribution the orbitofrontal cortex makes across the limbic, striatal, and prefrontal networks and discusses the implications of orbitofrontal dysfunction in addiction, aging, and psychiatric disorders. Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit for more information about becoming a member