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Pathogenic micro-organisms; a text-book of microbiology for physicians and students of medicine
This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 ... to 560 C., while the similar property of immune serum remains after this treatment. It is not yet conclusively proven that opsonins are separate substances entirely distinct from bacteriolysins and agglutinins, but it has been shown that opsonic power of a serum does not correspond to its concentration to that of the other antibodies, and some other element must, therefore, be a factor. Hektoen considers the opsonins to be distinct bodies, different from lysins and agglutinins. The study of opsonins has done much to bring about harmony between the followers of Metchnikoff, with their tendency to emphasize the importance of phagocytosis, and the followers of Buchner and Ehrlich, who fixed their attention largely upon the substances dissolved in the body fluids. Anti-aggressins, Specific Proteolysins.--Various substances produced in the body as a result of infection show particular ability to combat the effects of the soluble products of the parasite to which the name aggressins has been given (see page 205). Knowledge of these substances and their behavior is still somewhat incomplete, but they seem to be particularly concerned with the parental digestion of foreign proteins, a process in which cystolysis may be regarded as a beginning stage. Whereas, however, cytolysis is concerned with the disintegration of formed material, these substances now under consideration act particularly upon proteins already in solution. In many instances the products of the first stages in this parental digestion are toxic (disintegration of tuberculin and of egg-white), and some of the symptoms of infectious disease, such as fever, have been ascribed to them. In their general characters these lytic substances are wholly analogous to the cytolysins and their action is due to a...
140 pages, Paperback
First published August 24, 2013
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