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The Cell: A Molecular Approach

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The Cell presents current comprehensive science in a readable and cohesive text that students can master in the course of one semester. This new edition retains the overall organization, themes, and special features of the fourth edition, including Key Experiment and Molecular Medicine essays, chapter sidebars that highlight areas of interest and clinical applications, and end-of-chapter questions with answers at the back of the book. However, the fifth edition has been updated throughout to reflect major advances in the field since the publication of the fourth edition in 2006, including:
- Advances in understanding gene regulation by microRNAs
- Histones and epigenetic inheritance
- Identification of human disease susceptibility genes by genome-wide associaton scans
- Protein import into mitochondria
- Induced pluripotent stem cells
- Role of autophagy in programmed cell death
- Genomic analysis of mutations in human cancers
- New Key Experiments: RNA Interference (Chapter 4) and G Protein-Coupled Receptors and Odor Detection (Chapter 15)

820 pages, Hardcover

First published January 1, 1996

64 people are currently reading
824 people want to read

About the author

Geoffrey M. Cooper

29 books139 followers
Geoffrey M. Cooper is an award-winning author of medical thrillers and a 2023 Maine Literary Award Finalist in Crime Fiction. His experience as a former cancer researcher and scientific administrator, having held positions at Harvard Medical School and Boston University as professor, department chair, and associate dean, now provides extensive background for his novels. He lives in Ogunquit, Maine.

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5 stars
121 (44%)
4 stars
83 (30%)
3 stars
44 (16%)
2 stars
18 (6%)
1 star
8 (2%)
Displaying 1 - 20 of 20 reviews
Profile Image for sophia.
49 reviews
July 10, 2025
i’m adding this to my goodreads BC I READ THIS FROM START TO FINISH

all 20 chapters. the glossary. the index. even the table of contents (probably over 20 times)

textbook was not too great, it’s full of text blocks and over complicated at times. like why would you explain the full experiment behind a discovery in the middle of the sentence, without first explaining what that discovery is. i don’t need to know that AKT was discovered in mice, just tell me the pathway first!!!

barely any mention of plant biology (0/10).


overall, very enjoyable. maybe one of the few books that are over 700 pages that i’ve been so engaged with. the book tapped into my unlocked potential. also probably permanently changed my brain chemistry (for good or for bad, i’ll never know)

molcell2 was one of the best courses! now i will read real books and pray for my grade 🙏🏻
Profile Image for Rob.
86 reviews93 followers
March 31, 2009
lots of good illustrations, both schematic drawings with lumpy blobs for all the proteins and also really cool micrographs. i also liked the "key experiment" pages.

but the organization was bass ackwards. they started with chemistry, then DNA, then larger structures, until finally the cell cycle. so YOU NEVER KNEW THE BIGGER PICTURE. again and again, they would sort of hint at the larger context and then say "this is discussed in chapter 11" or whatever. the authors made the fatal mistake of so many teachers - they know the subject inside out, so they teach it from the inside out. it makes sense to them that way because they already know all the stuff from later chapters. but the student doesn't.

plus, they wrote with no personality at all. not one joke, anecdote, exclamation, etc., in the entire book.

finally, it was pretty clear that sometimes they wrote two pages and the publisher said "turn this into half a page" and so it became an ultradense series of technical sentences without explanation.

ah, well, i learned a ton, though. most interesting factoid: you can cut out two thirds of a rat's liver and it will grow back as good as new in a few days. wow.
Profile Image for Endi Tafani.
16 reviews1 follower
January 6, 2021
Horrible ,

it’s full of info , looks great and all but after a paragraph or two you can’t continue reading , your brain begs you to stop and it shuts down automatically.

You can’t even use it to sleep , sleeping after reading this brings horrific nightmares.

Profile Image for Deisy.
18 reviews2 followers
November 5, 2007
like it or not, this is an important book for PostGrad student like me... *sigh*
Oh well, let's just take it as a light reading... *lol*
Profile Image for Sofia Lavou.
1 review18 followers
September 9, 2014
The best book for cell biology.
Very illuminating and explanatory :)
It helped me a lot.
Profile Image for Niv.
19 reviews5 followers
August 3, 2011
best book for cell biology
27 reviews
May 8, 2024
I teach cell biology and wanted to try a new textbook with a better online platform for our students. I started out with a great attitude and wanted to love this book. I just got to where I hated it! It just had too many details and didn't do a good job breaking things down. The active learning exercises were stupid. I just didn't like it at all and my students liked it even less.
Profile Image for Eddie.
41 reviews2 followers
September 28, 2023
Mostly easy to understand and nicely written with informative pictures. But I kept wondering if the author just stopped repeating the same thing in different words how much shorter the chapters would be...
51 reviews
January 20, 2019
I can´t compare it to other book because i studied all from this one, but it was a really nice read
2 reviews
June 24, 2020
I don't understand the hype about this book. Tge illustrations are beyond good but the text is inferior
Profile Image for aby l.s.
161 reviews
July 7, 2024
Lean este antes que el Karp, es más terminología friendly 🙂‍↕️
Profile Image for robin.
20 reviews
Read
July 18, 2025
No me lo he leído entero pero espero aprobar biología después de haber estado trabajándome los capítulos que caían 🙏
Profile Image for ella.
19 reviews41 followers
November 19, 2025
Thanks for RUINING MY LIFE already. Too detailed
1 review
December 11, 2013
This is really helpful to increase my acknowledgement of basic science.
Displaying 1 - 20 of 20 reviews

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