Patrick Flynn's father dies, leaving him in charge or his younger sister, Katie, in 1901 New York City. Arranged by his father, Patrick embarks upon the Orphan Train, heading for a new home in the West. He meets and befriends Sarah the Sparrow, a street kid. There is also Jimmy the Brick and Scar Benny--a couple of mean Bowery boys. They taunt and abuse Patrick, making his life miserable. Patrick hopes to find a new family in the West, but is rebuked at every stop for various he is too old, too slight, too insistent on not parting with Katie. Even a tornado threatens to destroy his quest for a new home. Only upon arriving in Wichita, Kansas does Patrick find that which he is seeking. He and Katie begin fresh lives with a new family. And friends made aboard the train will remain friends forever. But will enemies remain enemies?