Antipsychotics

by John G. Csernansky

This volume summarizes recent advances in the understanding and development of new antipsychotic drugs from a wide variety of perspectives. Recent innovations in molecular biology and modeling offer a new array of neuroreceptor targets for drug development. Extensive investigations in neurophysiology, neurochemistry,and behavioral pharmacology have produced an understanding of antipsychotic drug action that goes far beyond the original dopamine hypothesis. Rather, new hypotheses about antipsychotic drug action are based on understanding the anatomy and activity of neuronal circuits.-Finally, this volume offers an expert summary of the characteristics that distinguish typical and atypical antipsychotic drugs, and the ways that these should be used in patients with schizophrenia and other mental disorders.

574 pages, Paperback

First published April 30, 1996