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Human Epigenomics
What is epigenomics?.- Methods and applications of epigenomics.- The structure of chromatin.- DNA methylation.- The histone code.- Chromatin modifiers.- Chromatin remodelers and organizers.- Embryogenesis and cellular differentiation.- Population epigenomics and aging.- Cancer epigenomics.- Neuroepigenetics.- Epigenomics of immune function.- Nutritional epigenomics.
244 pages, Paperback
Published March 16, 2020
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April 13, 2019
i am reviewing an online copy of this work which has been kindly provided by the publisher.
Epigenomics is a relatively new and emerging field and there are very few student text books in this area. Therefore the authors and the publisher are to be complemented for bringing up this volume to bridge the obvious gap.
The book is clearly written and presented and the chapters are well and logically organised. There are 13 chapters in all, the first part devoted to structural aspects and the second and concluding part to the many applications of epigenomics.
The important feature of the book, as brought out in the preface, is the importance given to human based studies in this field. Hence the book might apply to graduate students and reasearchers and also to clinical scientists.
For a difficult and new subject, the authors have adopted a balanced and integrative approach to the subject and the subject is introduced gradually. Hence, the initial chapters are devoted to the analysis of genetic apparatus of the human cell and nicely move on to the chromatin structure and function. The chapters are kept short probably to promote student understanding and they contain sufficient information for the advanced readers.
The second part is the more interesting one, because of the various applications of epigenomics studies. The chapters are woven around topics like Aging, Cancer, Nutrition and Immunity and they rightly discuss the roles of epigenomes in these critical areas.
However, I feel that the authors could have devoted some more attention to the gaps in our knowledge and could have pointed to areas which may gain prominence in the coming years. This could have aroused the interest of graduate students who can go on to further research in such areas.
The figures are good and accurate and properly convey the relationships among the different aspects of the epigenome. The language is clear and direct.
Overall, I consider this as a good synthesis of the current state of knowledge in this new and exciting field and it should serve advanced students and researchers well.
Epigenomics is a relatively new and emerging field and there are very few student text books in this area. Therefore the authors and the publisher are to be complemented for bringing up this volume to bridge the obvious gap.
The book is clearly written and presented and the chapters are well and logically organised. There are 13 chapters in all, the first part devoted to structural aspects and the second and concluding part to the many applications of epigenomics.
The important feature of the book, as brought out in the preface, is the importance given to human based studies in this field. Hence the book might apply to graduate students and reasearchers and also to clinical scientists.
For a difficult and new subject, the authors have adopted a balanced and integrative approach to the subject and the subject is introduced gradually. Hence, the initial chapters are devoted to the analysis of genetic apparatus of the human cell and nicely move on to the chromatin structure and function. The chapters are kept short probably to promote student understanding and they contain sufficient information for the advanced readers.
The second part is the more interesting one, because of the various applications of epigenomics studies. The chapters are woven around topics like Aging, Cancer, Nutrition and Immunity and they rightly discuss the roles of epigenomes in these critical areas.
However, I feel that the authors could have devoted some more attention to the gaps in our knowledge and could have pointed to areas which may gain prominence in the coming years. This could have aroused the interest of graduate students who can go on to further research in such areas.
The figures are good and accurate and properly convey the relationships among the different aspects of the epigenome. The language is clear and direct.
Overall, I consider this as a good synthesis of the current state of knowledge in this new and exciting field and it should serve advanced students and researchers well.
Displaying 1 of 1 review