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Cleanroom Technology: Fundamentals of Design, Testing and Operation

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A self-contained and practical book providing step-by-step guidance to the design and construction of cleanrooms, appropriate testing methodologies, and operation for the minimization of contamination… This second edition has been comprehensively revised and includes extensive updates to the two chapters that contain information on cleanroom standards and guidelines. The chapter on risk management has been extensively revised, especially the section on risk assessment. Other new subjects that have been added to the various chapters are those on clean-build, determination of air supply volumes for non-unidirectional airflow cleanrooms, RABS (Restricted Access Barrier Systems), contamination recovery test methods, entry of large items into a cleanroom, glove allergy problems, and how to develop a cleanroom cleaning programme. Used for in-house training and a textbook in colleges, this volume is for cleanroom personnel at all levels. It provides novices with an introduction to the state-of-the-art technology and professionals with an accessible reference to the current practices. It is particularly useful in the semiconductor, pharmaceutical, biotechnology and life sciences industries. William Whyte is an international authority in cleanrooms, with over 45 years experience in research, teaching and consulting in the electronic, healthcare and pharmaceutical industries. He is a member of British and International standards committees writing the International Cleanroom standards, and has received numerous awards for his work in Cleanroom Technology. A comment on the first edition: "...extremely useful and helpful...very well-written, highly organized, easy to understand and follow..." ( Environmental Geology , 2003)

384 pages, Hardcover

First published October 3, 2001

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William Whyte Jr.

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Displaying 1 - 3 of 3 reviews
16 reviews
March 12, 2017
A clear and very practical guide for setting up your own cleanroom. Easy to read, not too theoretical and with descriptions of the key steps for designing and operating a cleanroom.
6 reviews1 follower
February 27, 2023
A really good intro to cleanrooms. The first few chapters were really helpful to me as a background to design reasons and early operation. Some of the stuff seemed a bit too overdone and obvious to me, but could be useful to others. The garbing chapter was very informative to me as well.
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48 reviews
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September 12, 2025
Some concepts needs to implement, but author handles well, and he indeed covers numerous topics with underlying mechanisms. I loved it. Although first 9 topics could be a bit boring with many basics. I think the instructor is preparing you for the forward complexity. If you prefer more deductive method, glance chapter 15. Chapter 20, Mask and Glove is particularly great for me, with detailed explanations.
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