Studies on Vanadium Containing Model Complexes: Synthesis and studies on vanadium based complexes

by Nazmul Islam

Vanadium is an essential element in biological systems, participating in enzymic reactions. In addition, vanadate has shown great utility as a tool in molecular biology for recognizing and understanding the structure of phosphate binding proteins, by catalytic photocleavage of the peptide backbone. It is evidence that till now we are unable to study a bio molecule such as enzyme, protein chain, polypeptide etc, completely. To know the actual structure and function of the molecules, it is necessary to prepare some model compounds analogous to the bio-molecules of interest. V- compounds and vanadium-containing In this project, to study the vanadium protein interaction, an attempt was made to prepare model mixed ligand oxoperoxo compounds. Proteins may be intricately involved in vanadium binding in organisms. Peptides are the best one which most closely related models of proteins.Further, an attempt was made to prepare Oxovanadium (IV) complexes with Schiff's base. Mixed ligand peroxovanadium (V) complexes have also been attempted.

92 pages, Paperback

Published July 22, 2010