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“On Prozac, Sisyphus might well push the boulder back up the mountain with more enthusiasm and creativity. I do not want to deny the benefits of psychoactive medication. I just want to point out that Sisyphus is not a patient with a mental health problem. To see him as a patient with a mental health problem is to ignore certain larger aspects of his predicament connected to boulders, mountains, and eternity.”
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“The danger of academic life, thought Wittgenstein, is that we are encouraged to go on talking even when we know in our hearts that we have nothing valuable to say.”
― Slow Cures and Bad Philosophers: Essays on Wittgenstein, Medicine, and Bioethics
― Slow Cures and Bad Philosophers: Essays on Wittgenstein, Medicine, and Bioethics
“What makes our contemporary neurobiological concepts different is the extent to which they have been promoted by pharmaceutical marketers. You are not shy; you have social anxiety disorder. You are not absentminded, dreamy, or fidgety; you have ADHD. You are not moody; you are bipolar. Each diagnosis comes with a prescription. Your need for medication becomes part of your identity.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“We are led into philosophical confusion, thought Wittgenstein, by seeking explanations at times when we should instead simply stop and say, “This is how things are.”
― Slow Cures and Bad Philosophers: Essays on Wittgenstein, Medicine, and Bioethics
― Slow Cures and Bad Philosophers: Essays on Wittgenstein, Medicine, and Bioethics
“The very use of the term "mental illness" (rather than, say, "neurosis", "insanity", "nervous breakdown", or other euphemisms) can be seen as an effort to move certain kinds of psychological distress into the biomedical realm.”
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“This is not something you or I do. This is something the poor do so that the rich get better drugs.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“Medical care is neither a right nor a privilege: it is a service provided by doctors and other to people who wish to purchase it.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“Whether doctors and reps are all that different from each other is no longer clear. Doctors know a lot more about medicine, and drug reps dress a lot better, but these days both are Organization Men, small cogs in a vast health-care machine. They are just doing their jobs in a market driven health-care bureaucracy that Americans have deigned and that we define vigorously to critics elsewhere in the world. Like anyone else, doctors and reps are responding to the pressures and incentives of the system in which they work.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“As long as we live in a society in which a person’s own happiness is so dependent on the opinions of others, we will always have the problem of people feeling oppressed by cultural standards. We may be able to detach the problem from racism, so that beauty snobbery is racially egalitarian. We may be able to detach it from sexism, so that men are just as obsessed and fretful about their bodies as women are. We may be able to detach it from social biases against the short, the able-bodied, the gray-haired, and the wrinkled. But the problem will not go away. Like a particularly enthusiastic leech, it will find some other place to attach itself, and the deeper problem will remain untouched. That deeper problem is not simply the problem of racism or sexism (although those are problems too), but the fragility of selves that depend so intimately on the good opinions of others for their survival.”
― Better Than Well: American Medicine Meets the American Dream
― Better Than Well: American Medicine Meets the American Dream
“But there is a lot of fuzziness in the notion of "intellectual contribution." In some academic units, for example, junior scholars are expected to list their department chairs or lab chiefs as coauthors on all their publications, whether or not these people have actually contributed anything to the paper. In fact, I have heard some senior academics argue that they should be listed as coauthors on anything written by anyone being paid out of their grants. The polite term for this is honorary authorship or gift authorship, a practice that is officially frowned upon by journal editors but that remains relatively common.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“itself is becoming more and more commercialized. Beginning in the 1980s, a series of legislative initiatives pushed science and commerce much closer together, especially the Bayh-Dole Act, which (among other things) gave universities the right to profit financially from their scientific research. The purpose of these initiatives was to bring scientific discoveries to market faster, but it also encouraged scientists to behave like entrepreneurs—or, as Shapin might have it, for gentlemen to behave like merchants.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“The safety of new drugs has always depended on the willingness of someone to test them, and it seems inevitable that the job will fall to people who have no better options. Guinea-pigging requires no training or skill, and in a thoroughly commercial environment, where there can be no pretense of humanitarian motivation, it is hard to think of it as meaningful work. As Dave Onion puts it, “You don’t go home and say to yourself, ‘Now, that was a good day.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“To many critics, the main problem with medical ghostwriting is that academic physicians get credit for articles that they didn't actually write. the status of any academic for articles that they didn't actually write. The status of any academic depends heavily on his or her scholarship, and in academic medicine, the most important measure of scholarship is the sheer quantity of articles produced. The more papers a physician authors, the higher he or she elevates in the academic hierarchy. And if an academic physician is not actually doing the work behind the papers but is simply signing articles written by agency-employed medical writers, that physician's taking credit for the paper seems scandalous, like a student who buys paper on the Internet.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“In the culture of academic medicine, accepting credit for a ghosted journal article is not seen as a serious ethical failing, simply because the skill of writing is not seen as a valuable intellectual talent.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“Perhaps the most brazen ghostwriting campaign was that of GlaxoSmithKline, which came under fire for its promotion of the antidepressant Paxil as safe and non-habit-forming when evidence had linked the drug to an increased risk of suicidal ideation in children.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“The whole business of medical journals is corrupt because owners are making money from restricting access to important research, most of it funded by public money.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“During our early years of medical school, my classmates and I were given a course in physical diagnosis. Usually, we practiced on one another. Each of us would percuss a classmate’s chest or listen to his heart with a stethoscope. But some procedures were considered too personal to practice on a classmate. For some of these, we were assigned a “model patient”—someone from the community who was “compensated” in exchange for undergoing an examination. This was how I performed my first rectal exam. A large group of us were led into a room where our model patient was bent over an examining table with his pants around his ankles. One by one, we approached him nervously from behind, inserted a gloved, lubricated finger into his rectum, and felt around for the prostate. “Thank you,” we all said politely to the model patient as we removed our index fingers from his anus. The model patient stared straight ahead, saying nothing. What made the experience oddly disturbing was not just the forced, pseudo normality of the instruction or the fact that the exam could have been done more privately, but the instrumentality of the encounter: a pretend patient bending over naked for anonymous strangers in exchange for money. The fact that the model patient had been paid did not make his work seem any less degrading. (Tipping him would have made it even worse.)”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“Over the past twenty years, the evidence that gifts and payments have a profound influence on doctors has become virtually indisputable. Doctors who are paid by a company are more likely to write prescriptions for that company’s drugs, more likely to give talks that are favorable to the company, and more likely to produce research that benefits the company.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“As the figure of the traditional doctor fades away, it is being replaced by a figure to the drug rep, one whose responsibility is to compete as vigorously as possible in the medical marketplace. Patients are being replaced by health-care consumers, who shop for the best medical bargains they can find.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“Meanwhile, our patchwork regulatory system insures that no single institution is keeping track of how many deaths and injuries befall healthy subjects in clinical trials. Nobody appears to be tracking how many clinical investigators are incompetent of have lost their licenses, or have questionable disciplinary records.. Nobody is monitoring the effect that so many trials have on the health of professional guinea pigs. In fact, nobody is even certain whether the trials generate reliable data.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“As our culture has shifted the locus of meaning in life away from God and onto individual psychology, we have created a moral yardstick that measures the success of a human life in terms of psychological well-being. As”
― Better Than Well: American Medicine Meets the American Dream
― Better Than Well: American Medicine Meets the American Dream
“In America I have seen the freest and best educated of men in circumstances the happiest to be found in the world, yet it seemed to me that a cloud habitually hung on their brow, and they seemed serious and almost sad even in their pleasures.”
― Better Than Well: American Medicine Meets the American Dream
― Better Than Well: American Medicine Meets the American Dream
“In The Triumph of the Therapeutic, Philip Rieff famously argued that the typical American has come to think of himself less as a citizen than as a kind of patient, whose life purpose is to develop, sustain, and fine-tune his psychological well-being. For Rieff, this therapeutic turn is a logical consequence of civic and spiritual decline. Somehow our sense of the purpose of living has slipped out of joint from the social conditions that once sustained it. We are no longer at home with ourselves, never quite comfortable with our place in the world. Instead, we are like castaways on a strange island, unfamiliar with local conditions, unable to rely on the old ways of going on. Perhaps something about the way we live now produces this distance from one another, or perhaps we distance ourselves from one another and live the way we do as a result. Either way, we have become more narcissistic, but narcissistic in a way that is peculiarly dependent on things outside ourselves: that is to say, what other people are saying and thinking about us. Rieff puts it this way, “When so little can be taken for granted, when the meaningfulness of social existence no longer grants an inner life at peace with itself, every man must become something of a genius about himself.”33”
― Better Than Well: American Medicine Meets the American Dream
― Better Than Well: American Medicine Meets the American Dream
“More important, prescription tracking helped reps figure out which doctors to target. They no longer had to waste time and money on doctors with conservative prescribing habits; they could head straight to the high prescribers, or high writers.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
“The more papers a physician authors, the higher he or she elevates in the academic hierarchy. And if an academic physician is not actually doing the work behind the papers but is simply signing articles written by agency-employed medical writers, that physician’s taking credit for the paper seems scandalous, like a student who buys a paper on the Internet. “I don’t feel really good about ghostwriting an article that is going to appear under the name of a doctor at Brown University who is going to get twenty-five hundred dollars to do nothing more than review it,” says Susan Gilbert, a writer who worked briefly for a medical communications agency before going into bioethics. “The whole structure of the business was wrong to me.”
― White Coat, Black Hat: Adventures on the Dark Side of Medicine
― White Coat, Black Hat: Adventures on the Dark Side of Medicine





