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“When people with ME/CFS report symptoms of post-exertional malaise, those symptoms are independent of emotional distress, but when the general population report what they think are post-exertional malaise symptoms, their symptoms of post-exertional malaise are significantly related to emotional distress. It is possible that because healthy individuals experience a relationship between emotional distress and post-exertional malaise, they might believe that these two domains are connected for themselves and by inference with patients with ME/CFS, when in fact it is not the case. This ultimately might blur the ability of healthy controls to understand the experience of post-extertional malaise for people with ME/CFS.”
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“Severe, persisting fatigue is a prominent symptom of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), but individuals with this illness frequently report the occurrence of unique fatigue states that might be different from conventional symptoms of fatigue.”
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“Finally, individuals with severe pathological fatigue might experience states that are very different from what a healthy individual experiences when fatigued.”
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“the disabling fatigue experienced by individuals with ME/CFS differs from that associated with other illnesses or everyday activity”
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“The finding that ME and CFS group had more functional limitations and more serious symptoms than those with MS [multiple sclerosis] provides additional evidence to the seriousness of ME and CFS.”
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“individuals with ME/CFS experience different types of fatigue than what are reported in the general populations”
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“Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition characterized by severe unexplained fatigue and a mixed profile of symptoms such as sore throat, painful/swollen lymph nodes, muscle pain, joint pain, headaches, unrefreshing sleep, post-exertional malaise and cognitive difficulties (K. Fukuda et al., 1994).”
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