Matt Simon

“Mothers not only pass the harms of endocrine-disrupting chemicals on to their fetuses but on to even more distant generations. When a mother is exposed to EDCs, so too are her fetus's germ cells, which develop into eggs or sperm. "It's thought that during that exposure, the chemical can target those germ cells and do what we call reprogramming, or making epigenetic changes," says Flaws. "That can be a permanent change that gets carried through generations, because those germ cells will eventually be used to make the next generation, and those fetuses will have abnormal germ cells that would then go on to make the next generation." In the mid-20th century, scientists documented this in women who took a synthetic form of estrogen, called diethylstilbestrol or DES, to prevent miscarriages.? The drug worked as intended, and the women gave birth to healthy babies. But once some of those children hit puberty, the girls developed vaginal and breast cancer. The boys developed testicular cancer, and some suffered abnormal development of the penis. Scientists called them DES daughters and sons. "When those DES daughters and sons had children, we now have DES granddaughters and grandsons, and a lot of them have increased risk of those same cancers and reproductive problems," says Flaws. "Even though it was their great-grandmother that took DES and they don't have any DES in their system-their germ cells have been reprogramming, and they're passing down some of these disease traits." And now toxicologists are gathering evidence that mothers are passing microplastics and nanoplastics complete with EDCs and other toxic substances- to their fetuses. In 2021, scientists announced that they'd found microplastics in human placentas for the first time, both on the fetal side and maternal side.Later that year, another team of researchers found the same, and they also tested meconium-a newborn's first feces and discovered microplastic there too. Children are consuming microplastics, then, before they're even born.”
― Matt Simon, A Poison Like No Other: How Microplastics Corrupted Our Planet and Our Bodies