“I would also exercise caution when mixing SSRI antidepressants and microdoses of psilocybin because they both affect the serotonin system in the brain. While an adverse reaction combining SSRIs with a microdose isn’t likely according to Fadiman’s site, as we’ll discuss in Chapter 14, these kinds of antidepressants can lessen the effects of full-dose psychedelics and will likely do the same with microdoses.”