“What people specifically should not take them?” like this: “People who are mentally unstable, under enormous pressure, or operating equipment that the lives of hundreds of people depend on. Or the fragile ones among us—those to whom you wouldn’t give a weekend airline ticket to Paris, those who wouldn’t expect to guide you out of the Yukon. Some people have been so damaged by life that boundary dissolution is not helpful to them. These people are trying to maintain boundaries, their functionality. They should be honored and supported, and not encouraged to take drugs. If because of genetic or cultural or psychological factors it’s not for you, then it’s not for you.”