“The basic concept of microdosing is nothing new. Albert Hofmann, who first synthesized LSD in 1938, considered it one of the drug’s most promising, and least researched, applications. He was among the first to realize its antidepressant and cognition-enhancing potential,[vi] famously taking between 10 and 20 μg himself, twice a week, for the last few decades of his life.[vii]”