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  • #1
    Alex Korb
    “Making a decision, even a tiny decision, starts shedding light on ways to improve your life.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #2
    Alex Korb
    “Shift your focus to what’s occurring right now. This is why Buddhist monks and yogis practice nonjudgmental awareness—the process of being aware of the present, without attaching emotional reactivity to it. This mindfulness practice cuts off worry and anxiety at the source.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #3
    Alex Korb
    “Acceptance, on the other hand, teaches that how you feel is simply how you feel. It’s neither good nor bad. It just is. And interestingly, when you’re stewing in negative emotions, accepting them often helps them dissipate, like an early morning mist beneath a ray of sun.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #4
    Alex Korb
    “My life has been full of terrible misfortunes, most of which never happened.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #5
    Alex Korb
    “You can change dopamine and the dorsal striatum with exercise. You can boost serotonin with a massage. You can make decisions and set goals to activate the ventromedial prefrontal cortex. You can reduce amygdala activity with a hug and increase anterior cingulate activity with gratitude. You can enhance prefrontal norepinephrine with sleep.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #6
    Alex Korb
    “In particular, aerobic exercises, like running and biking, are best at boosting serotonin. Interestingly, if you try to do too much exercise or feel forced to do it, it may not have the right effect.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #7
    Alex Korb
    “In a commencement address in 2012, author and graphic novelist Neil Gaiman made the keen observation that “if you’re making mistakes, it means you’re out there doing something.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #8
    Alex Korb
    “Stay in the now. Pay attention to the things that are happening now, and don’t pay attention to the things that aren’t happening now. Focusing on the present helps reduce anxiety and worry, because it decreases emotional, self-focused processing in the ventromedial prefrontal cortex. Attention to the present also increases dorsolateral and ventrolateral prefrontal activity, allowing these regions to calm the amygdala.15 Improving your ability to stay present, a practice known as “mindfulness,” helps enhance these activations and leads to long-term improvements in anxiety and worrying.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #9
    Alex Korb
    “Serotonin—improves willpower, motivation, and mood. Norepinephrine—enhances thinking, focus, and dealing with stress. Dopamine—increases enjoyment and is necessary for changing bad habits. Oxytocin—promotes feelings of trust, love, and connection, and reduces anxiety. GABA—increases feelings of relaxation and reduces anxiety. Melatonin—enhances the quality of sleep. Endorphins—provide pain relief and feelings of elation. Endocannabinoids—improve your appetite and increase feelings of peacefulness and well-being.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time

  • #10
    Alex Korb
    “Fortunately, suppressing an impulse doesn’t always have to decrease your dopamine—it can actually feel good. The key is the prefrontal cortex, which is responsible for pursuing long-term goals and has the ability to modulate dopamine release in the nucleus accumbens. So suppressing an impulse can be rewarding, as long as it’s in service of your larger values.”
    Alex Korb, The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time



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