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Mark Henkel
Mark Henkel is on page 56 of 496 of Outlive: The Science & Art of Longevity
Ch.3 Complete
OBJECTIVE, STRATEGY, TACTICS
A Roadmap for Reading this Book

Strategy from 5 data sources:
centenarians
lifespan of "animal models"
human studies of 4 Horsemen
molecular & mechanistic studies of human & animal models (to drugs & exercise)
MR (Mendelian Randomization)

Like investment tactics for best ROI
get better than avg returns with acceptable risk,'
called ALPHA.

Achieve your own LONGEVITY ALPHA
8 hours, 36 min ago Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 56 of 496 of Outlive: The Science & Art of Longevity
Ch.3 Complete
OBJECTIVE, STRATEGY, TACTICS
A Roadmap for Reading this Book

x = Lifespan
y = Healthspan

Last decade > "Marginal Decade"

"Living longer means delaying death from ALL 4 of Horsemen
(cancer, diabetes, cardiovascular disorsers, & neurodegenerative diseases"

3 vectors or deterioration:
cognitive
physical
emotional health

5 Med 3.0 tactics:
exercise
nutrition
sleep
emotional health
exogenous molecules
8 hours, 42 min ago Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 36 of 496 of Outlive: The Science & Art of Longevity
Ch.2 Complete
MEDICINE 3.0
Rethinking Medicine for the Age of Chronic Disease

"Medicine 3.0 pays far more attn to mantaining healthspan, the quality of life"

"Longevity, itself,
and healthspan in particular,
doesn't really fit into the business model of our current healthcare system"

"money flows to treatment rather than prevention" (<--EXACTLY!)
8 hours, 49 min ago Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 36 of 496 of Outlive: The Science & Art of Longevity
Ch.2 Complete
MEDICINE 3.0
Rethinking Medicine for the Age of Chronic Disease

Medicine 1.0 = conclusions based on observations & guesswork
(no by more by "the gods")

2.0 = mid1800s - germ theory of disease, adding hypothesis to steps
AFTER DISEASE NOTED
100yrs less successful against longterm disease like cancer

3.0 = prevent tumors (etc) starting spreading in first place
emphasis: PREVENTION, quality of life
8 hours, 52 min ago Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 20 of 496 of Outlive: The Science & Art of Longevity
Ch.1 Complete
THE LONG GAME
From Fast Death to Slow Death

Epitaph same as
"UPSTREAM" by D.Heath

Longevity - 2 components"
*how long you live
*how well you live

"Death rates from cancer...
hardly budged in more than 50 years...
despite 100s of Billions spent on research"

"Medicine's biggest failing...
treat conditions... AFTER (disease) is entrenched
rather than before"

Protein so important

PRACTICE of Longevity
Feb 02, 2026 07:43PM Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 4 of 496 of Outlive: The Science & Art of Longevity
Introduction Complete

"Dream of the falling eggs"
Feb 01, 2026 07:32PM Add a comment
Outlive: The Science & Art of Longevity

Mark Henkel
Mark Henkel is on page 308 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
.
Pp.271 - 298 Notes (read as book read)
Pp.299 - 307 Index
Jan 31, 2026 07:15PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 270 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Ch.11 Complete
After the Overruling of Roe: The Natural Law Movement

Dobbs v. Jackson
was
less fundamental for pro-lifers
&
not as devastating as pro-abortionists feared.

"On the substantive rights or wrongs of abortion,
conservative jurisprudence had nothing to say"

"value judgments" replaced obvious NL "moral truths"

so issue back to the states to set own "value judgments"

as both sides could make return to NL
Jan 31, 2026 07:14PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 233 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Monday, January 26, 2026
Ch.10 Complete
The Moral Turn in Jurisprudence

A 25-page run-down of cases and arguments
that led to the SCOTUS decision of
Roe v. Wade
and the impact to NL.
Jan 27, 2026 07:14PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 207 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Ch.9 Complete
Recasting Religious Freedom

J.Madison's "Memorial & Remonstrance against Religious Assessment" (1785)
"this right [of religious freedom] is in its nature an unalienable right"

The moral reasoning of the NL

Reynolds v US
"legitimate religion in America"
polygamy

to satisfy the non-religious, conservs backed off legit vs illegit

RFRA

NL in play when we test "justifications" for restricting freedoms
Jan 24, 2026 08:43PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 171 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Ch.8 Complete
The Conservatives and the Lure of Defensive Relativism:
Spiraling Down

Matal v Tam (2017) The Slants

Speech may not be banned on ground it expresses ideas that offend

offense is subjective

A.Lincoln: only rightful govt depends on consent of the government

"Choosing to elect Nazis" is to legit Party that would end elections

moral relativism

Conservatives backed themselves into spiral of relativism
Jan 17, 2026 08:52PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 157 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Ch.7 Complete
Speech and the Erosion of Relativism

One man's vulgarity another man's lyric

If moral judgments rested on mere feelings,
how could one ever have a MORAL ARGUMENT?

Our language reflects our nature as moral beings

Convoluted twists of SCOTUS decisions
of allowed/disallowed speech

pro-life
racism

Hitler: "conquest of the streets"

Heckler's Veto

"Homophobe" slur to shut down

words to incite fighing
Jan 15, 2026 06:50PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

Mark Henkel
Mark Henkel is on page 125 of 336 of Mere Natural Law: Originalism and the Anchoring Truths of the Constitution
Ch.6 Complete
On Civil Rights: Theories in Search of a Principle

"DIF between real principles & merely 'contingent propositions'"

"We cannot hold people accountable for acts they powerless to effect"

"racial discrimination denies black people as moral agents to bear responsibility for own acts"

Racial quotas betray that categorical truth by "allowing" diversity racism

No way for categorical wrong to be justified
Jan 11, 2026 07:01PM Add a comment
Mere Natural Law: Originalism and the Anchoring Truths of the Constitution

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