Blog #177: Heart Attacks, Strokes and cardiovascular Dangers From Epilepsy Drugs

 




 

Enzyme-inducing antiepileptic drugs (EIAEDs) are a class ofmedications used to manage seizures that also have the effect of increasing theactivity of certain liver enzymes, primarily the cytochrome P450 (CYP450)family

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How Enzyme Induction Works:

•          EIAEDsstimulate the production of CYP450 enzymes in the liver.

•          Theseenzymes are responsible for metabolizing (breaking down) many drugs and othersubstances in the body/

Carbamazepine (Tegretol), Phenytoin (Dilantin),Phenobarbital (Luminal),and Primidone (Mysoline) are the classicalenzyme-inducing antiseizure drugs (ASDs). Non-enzyme-inducing ASDs includeLevetiracetam (Keppra), Lamotrigine (Lamictal),Lacosamide (Vimpat).


Lance Fogan, M.D. is Clinical Professor of Neurology at the David Geffen School of Medicine at UCLA. His hard-hitting emotional family medical drama, “DINGS, is told from a mother’s point of view. “DINGS” is his first novel. Aside from acclamation on internet bookstore sites, U.S. Report of Books, and the Hollywood Book Review, DINGS has been advertised in recent New York Times Book Reviews, the Los Angeles Times Calendar section and Publishers Weekly. DINGS teaches epilepsy and is now available in eBook, audiobook, soft and hard cover editions.

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Published on May 25, 2025 05:00
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