After running a 7.5-million-year program, a fictional super computer says the answer to the meaning of life, the universe, and everything is…wait for it…42. For the forty-six years since that novel was published, fans have been speculating as to the meaning of 42. Looking so hard for certainty, we miss the point. The author said publicly that the number was completely random, chosen for its insignificance. Making the point that any rational answer to the meaning of life is itself meaningless.

My...