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Pathogenesis
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March 2026 - Pathogenesis
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I just started it. The wait list at my library was pretty long. I love that he started off with references to both The Lord of the Rings and Harry Potter. And then he argues against Yuval Noah Harari. Good stuff. But I'm not very far in.
This is next on my audio book list. I'm about 85 % done with my current book so should be able to begin soon.
I'm about 3/4 of the way through the book at this time, and will probably finish it soon.Sticking with the first chapter for now, I was happy to see him take on Yuval Noah Harari’s assertion that there was a leap in Homo Sapiens cognition that led to their migration into Europe to compete/absorb/replace the Neanderthals . Kennedy's idea that the Homo Sapiens migration was enabled by a climate-driven increase in acquired immunities while Neanderthals had relatively lower immunity as thinly populated hunter/foragers seems reasonable. But he also does not reference any specific evidence, other than that's just how pathogens work. So it's just speculation versus speculation. Did I miss something?
I agree. I'm still not very far in. But that was also my objection to Harari. Lack of evidence. It seems to me Kennedy's evidence is a little more compelling -- DNA. But this is not my field, so I don't know how to judge it. And it's not quite direct.
I finished this a few days ago and I'm of two minds. On the one hand it's super comprehensive and written by an author with a PhD in sociology who now teaches global health. It's cited, there are some good sounding arguments, and it's engaging. On the other hand, the "eight plagues" are actually time periods rather than specific pathogens, and the book is Eurocentric despite Kennedy calling out Eurocentrism in scientific theories. Additionally, it's advertised as a hard science book but it's more of a social science history book.
I've finished the book yesterday, and am still thinking about what I want to say in a review.@Betsy: It's also not my field, but I think the DNA evidence he describes points strongly at the timeframe of the Homo Sapiens migration into Europe, rather than the "why then" of it.
@J. I also have some ambivalence about it being more of sociology/economics read than a science read. I would take what you say about Eurocentrism a step further, and call it Anglocentric - especially that chapter on the English Industrial Revolution.
Tomislav wrote: "I've finished the book yesterday, and am still thinking about what I want to say in a review.@Betsy: It's also not my field, but I think the DNA evidence he describes points strongly at the timef..."
See, I appreciate a good social science as much as a hard science and think those topics are just as important for us to read in this group. My main issue was in how the book sets up the expectation of its content for the reader, which then does the work a disservice.
And regarding the Anglocentrism, honestly you're probably right to suggest it's actually worse than I wrote. Which again does the work such a disservice because the reader is expecting a history of "the world" not "the world insofar as it's part of the British Commonwealth".
The final chapter of the book is mostly oriented towards advocacy of collective government action in matters of public health (with which I strongly agree). However, he cites a falsely low death rate from covid in China where strong intervention was enforced. "Although China was the original source of Covid-19, the pandemic has killed fewer than 15,000 people there, according to official statistics: 0.001 percent of the population." The book was written in 2023, and his data may have been preliminary, but the reality is much different from that. Today I found on wikipedia that "The number of reported deaths and cases in China is likely severely undercounted. Multiple independent studies estimate China's true COVID-19 death toll may be between one to two million, rather than the official count of 122,398.[12][13] This is partly due to how deaths caused by COVID-19 are counted. Only deaths occurring in hospitals are included.[14] Furthermore, regional disparities in reporting and sudden changes in testing strategy contributed to challenges in determining the actual mortality burden." China's rate is still a lot lower than that experienced in the US for example, but nowhere near as extremely so.
I finished this a few days ago. I enjoyed it, but I agree with J. that it was somewhat misrepresented. Here is my review.
I finally finished this book. It is a really good read, and I learned (or re-learned) a lot from it. Here is my review.
message 14:
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aPriL does feral sometimes
(last edited May 31, 2026 11:48AM)
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rated it 4 stars
I am starting the book today. I have a feeling of irony in doing so. My interest is much more intense today than it might have been a few months ago, whatever the book’s shortcomings.I am recovering from Covid. This makes the third time. The first time was November, 2020, no vaccine available. My experience was having a terrible cough cold. I have since been vaccinated with every one announced, the boosters, the new strains.
The second time, I was unaware I had it because I had no symptoms. I tested myself because my spouse came down with obvious symptoms, testing positive for Covid.
This month, May 2026, I have been horribly sick with more “classic” Covid symptoms, such as loss of taste and smell, first time for me. I am hoping I also don’t get “long Covid”, whatever that is, since I seem to have become infected with a strain giving me a lot of what has been publicized.
I’ve read the introduction so far. Right now, I’m feeling kinda mean towards viruses. 🤧
aPriL does feral sometimes wrote: "I am starting the book today. I have a feeling of irony in doing so. My interest is much more intense today than it might have been a few months ago, whatever the book’s shortcomings.
I am recover..."
So sorry you're sick. Covid has been so weird. I've never had it. Others get it multiple times. Then there's long covid, which from what I can tell is very unusual in epidemiology.
I don't think this book will help you feel better, but it's interesting.
I am recover..."
So sorry you're sick. Covid has been so weird. I've never had it. Others get it multiple times. Then there's long covid, which from what I can tell is very unusual in epidemiology.
I don't think this book will help you feel better, but it's interesting.
message 17:
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aPriL does feral sometimes
(last edited Jun 11, 2026 10:05PM)
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rated it 4 stars
Whatever the book’s defects, to me they are minor minor minor. I really liked the book, and I learned a lot from it. It put into a solid fact-checked (mostly, or at least into a reasonable reasoned theory) narrative and all related connected info in a single book things which I have wondered about in a lifetime of reading about health issues and pollution effects, especially in poor countries and in poor neighborhoods everywhere in the world. For decades, as a magazine and newspaper reader, I came across this article or that story. Here, it is all in one place. It connects the education and culture and politics of communities which influence health outcomes, which is how I’ve always argued my points when in conversation with people. Perhaps this is how I’ve always wanted my science information because I grew up during the Vietnam War, a very fraught time of everything under America’s social, economic and cultural sun being overturned.About the Covid epidemic: what is disgusting to me is it appears ‘the common American man’ has not been ‘uplifted’ into science knowledge or have trust in scientists when scientists have been double-checked and triple-checked on their work. I read a lot, and this has separated me from my peers who are suspicious of vaccines, or even have trouble believing covid is a real disease or if a secret deep liberal program to poison Americans. The fact that the conclusions people had in their eras with the origins of Black Death and ‘cures’ aren’t any different than today’s in my peer group and family is awful. Many of my relatives are religious, and many believe right-wing conspiracy theories. Dying from a disease is considered from some people I know to be god’s will, so don’t fight it by getting vaccines, and go to church and pray shoulder to shoulder with your unmasked community. And so on….
The fact that part of the book focuses occasionally on the deficiencies of England’s handling of health problems does not stop me from easily noticing these issues apply to the similar deficiencies of other first-world governments, such as my home country. I can easily extrapolate the simularities from reading for the past few decades the on-line magazines and newspapers. In the 1970’s, we high school kids were taught the exact same info as given in the book about how colonialism destroyed economies of third-world countries, so this information was not new to me. What was new to me was how malaria affected the colonial powers in Africa, and how different the history of colonialism affected many third-world countries in comparison to America’s. I always had wondered why America had a successful revolution and why African nations, many of which also revolted against European powers, did not.
Btw, I’ve been reading about the troubles of health officials in the Congo, and it leaves me full of despair. The locals think NGO’s are lying about the ebola disease, because they want the organs. They also think witchcraft is involved. FFS!
Books mentioned in this topic
Pathogenesis: A History of the World in Eight Plagues (other topics)Authors mentioned in this topic
Yuval Noah Harari (other topics)Jonathan Kennedy (other topics)




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