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Pediatric Pulmono...
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“Cycle asynchrony is present when the ventilator inspiratory (Ti-vent) and expiratory times are different from that of the patient’s neural inspiratory (Ti-pt) and expiratory times. Double cycling in VCV suggests that the patient is still inspiring when the ventilator is turned off (Ti-pt>Ti-vent). Lengthening inspiratory time by adding an inspiratory pause or reducing flow may help, as might increasing VT. An end-inspiratory spike in the pressure-time waveform suggests that the patient is trying to exhale, while the ventilator is still pushing (Ti-pt < Ti-vent); increasing the set flow or reducing VT might alleviate this. The PCV may be helpful in this situation, but the inspiratory time is still constant and may not be comfortable. A trial of high-level PS might be attempted, although some new ventilators allow PCV to be flow cycled and to function like PS with a backup rate.”
Anonymous

“A ventilator mode that automatically adjusts inspired volume on the basis of the patient’s actual respiratory mechanics is intriguing and may help to minimize iatrogenic lung injury, particularly in settings where constant vigilance and frequent manual adjustment are not practical.”
Anonymous

“Clinicians set a target minute ventilation, and the ventilator determines an optimal VT and rate combination that result in the least work of breathing, based on the “minimum work of breathing” concept described by Otis et al.53 Theoretically, when the patient’s compliance is reduced (ie, has ALI), a smaller VT and faster rate are chosen, whereas in patients with obstructive lung disease, a larger VT and slower rate are chosen to minimize air trapping. There is concern that large VTs and high pressure may also increase the risk of developing ALI or ARDS in patients without lung disease.”
Anonymous

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