“Mechanical stress on the bone produced a piezoelectric signal from the collagen. The signal was biphasic, switching polarity with each stress-and-release. The signal was rectified by the PN junction between apatite and collagen. This coherent signal did more than merely indicate that stress had occurred. Its strength told the cells how strong the stress was,and its polarity told them what direction it came from. Osteogenic cells where the potential was negative would be stimulated to grow more bone, while those in the positive area would close up shop and dismantle their matrix. If growth and resorption were considered as two aspects of one process, the electrical signal acted as an analog code to transfer information about stress to the cells and trigger the appropriate response.Now we knew how stress was converted into an electrical signal. We had discovered a transducer, a device that converts other forces into electricity or vice versa.”
― The Body Electric: Electromagnetism and the Foundation of Life
― The Body Electric: Electromagnetism and the Foundation of Life
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