Julie
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Julie

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Alice Hoffman
“It was believed that all creation came from thought, language, and mathematics.”
Alice Hoffman, The World That We Knew

“Cordon sanitaire. Isolation. Quarantine. These are age-old concepts that human beings have been putting into practice since long before they understood the nature of the agents of contagion, long before they even considered epidemics to be acts of God. In fact, we may have had strategies for distancing ourselves from sources of infection since before we were strictly human.”
Laura Spinney, Pale Rider: The Spanish Flu of 1918 and How It Changed the World

“Most of the death occurred in the thirteen weeks between mid-September and mid-December 1918. It was broad in space and shallow in time, compared to a narrow, deep war.”
Laura Spinney, Pale Rider: The Spanish Flu of 1918 and How it Changed the World

“It was a fascinating hint that flu might have a heritable component, but other studies failed to replicate the finding. Then in January 2011, in the midst of the annual flu season in France, a two-year-old girl was admitted to the intensive care unit of the Necker Hospital for Sick Children in Paris, suffering from ARDS (acute respiratory distress syndrome). Doctors saved her life, and one of them, Jean-Laurent Casanova, sequenced her genome. He wanted to know if it held the key to why an otherwise healthy child had nearly died of a disease that most children shrug off. It turned out that the girl had inherited a genetic defect that meant she was unable to produce interferon, that all-important first-line defence against viruses. As a result, her besieged immune system went straight to plan B: a massive inflammatory response similar to the one pathologists saw in 1918.”
Laura Spinney, Pale Rider: The Spanish Flu of 1918 and How It Changed the World

“Whereas a benign, seasonal virus produced a transient cytokine response and localised, superficial damage to the lung, the 1918 variety produced a strong, prolonged cytokine response and damage that was severe and deep.”
Laura Spinney, Pale Rider: The Spanish Flu of 1918 and How It Changed the World

109587 Ask Kathy Reichs - Sunday, August 25th! — 779 members — last activity Jul 08, 2015 02:20AM
Join us on Sunday, August 25th for a special discussion with author Kathy Reichs! Kathy will be discussing her newest book Bones of the Lost. Bec ...more
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