David Mintz

“Human life must be some kind of mistake. The truth of this will be sufficiently obvious if we only remember that man is a compound of needs and necessities hard to satisfy; and that even when they are satisfied, all he obtains is a state of painlessness, where nothing remains to him but abandonment to boredom. This is direct proof that existence has no
real value in itself; for what is boredom but the feeling of the emptiness of life? If life—the craving for which is the very essence of our being—were possessed of any positive intrinsic value, there would be no such thing as boredom at all: mere existence would satisfy us in itself, and we should want for nothing.”
― Arthur Schopenhauer, Studies in Pessimism: The Essays

“Schizophrenia cannot be understood without understanding despair.”
― R.D. Laing

“The artist's job is not to succumb to despair but to find an antidote for the emptiness of existence.”
― Woody Allen, Midnight in Paris: The Shooting Script

“Whether you are man or woman, rich or poor, dependent or free, happy or unhappy; whether you bore in your elevation the splendour of the crown or in humble obscurity only the toil and heat of the day; whether your name will be remembered for as long as the world lasts, and so will have been remembered as long as it lasted, or you are without a name and run namelessly with the numberless multitude; whether the glory that surrounded you surpassed all human description, or the severest and most ignominious human judgment was passed on you -- eternity asks you and every one of these millions of millions, just one thing: whether you have lived in despair or not, whether so in despair that you did not know that you were in despair, or in such a way that you bore this sickness concealed deep inside you as your gnawing secret, under your heart like the fruit of a sinful love, or in such a way that, a terror to others, you raged in despair. If then, if you have lived in despair, then whatever else you won or lost, for you everything is lost, eternity does not acknowledge you, it never knew you, or, still more dreadful, it knows you as you are known, it manacles you to yourself in despair!”
― Søren Kierkegaard, The Sickness Unto Death: A Christian Psychological Exposition for Upbuilding and Awakening