Status Updates From Viruses: A Very Short Intro...

Smallpox: Ethiopia was last endemic
Rinderpest: mortality was 90%; last case was in kenya
TTV like miniviruses are carried by nearly everyone and are harmless
Measles SSPE is 1 in 10,000
there are 8 human herpesviruses
UV light can precipitate HSV cold sores
10% fetus are affected by primary maternal CMV
EBV: asymptomatic in child; GF in 25% non child; GF lasts 10-14 days; GF

rotavirus: 10 virions can infect; kills 440,000 annually
influenza: usually >7 days
rubella: bad in 10-16 weeks pregnancy
norovirus kills 50,000 annual
polio: bad in 1 in 1,000; non paralytic is meningitis; 5% paralytic is fatal; became a problem when maternal immunity decreased through hygiene; 1/million live vaccine cause paralytic; still in pakistan and afghanistan

rinderpest is closest to measles
smallpox had 30% mortality
measles needs 500,000 people to circulate

SARS CoV 2 initially had 25% mortality for over-85

MERS mortality rate is 35%
MERS is from camels “camel flu”
There are 4 minor coronaviruses and 3 serious coronaviruses
Zika is mainly only a problem in pregnancy
Chickungunya means “the one which bends up” because the joint pain makes you stoop
dengue is called “break bone fever”
1-2% dengue cases are serious
yellow fever has 50% mortality