Sophia’s Reviews > Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six > Status Update

Sophia
Sophia is on page 225 of 501
Issue #339 -
Caeser's plan worked. MJ met with him at the abandoned set...

Turns out though, the cop that was helping MJ is her 'biggest fan'... and is NOT a cop!

The end sees MJ saving herself and Ock finally believing Spidey when he goes for the Burundite canister instead.


Not a bad story line. I think just a little lacklustre after seeing a more dramatic Sinister Six fight on screen.
Jan 27, 2026 07:52PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six

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Sophia’s Previous Updates

Sophia
Sophia is on page 202 of 501
Issue #338 -
Peter gives his Aunt May a little bit of comfort.

Meanwhile, Jonathan Ceaser is making plans to be reunited with MJ…

Hilariously, MJ made a comment about so many costumed heroes being around.

The Sinister Six crash the rocket launch!

Sandman refuses to kill an innocent while Doc Ock kills an engineer to ensure the rocket launches with the poison.

Then... Hobgoblin poisons Spider-Man!
Jan 27, 2026 07:05PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 178 of 501
Issue #337 -
We learn Doc Ock’s plan is… to hold the entire Earth for ransom!

He says so the Sinister Six can all rule together but of course, that’s not the truth.

Firstly, Pete and MJ walk down a street (Wolverine & Punisher cameo?) then show us what a healthy relationship looks like.

Then Flash takes on goons for Felicia.

Anyway, Spidey’s not having a good day and every villain gets away from him!
Jan 27, 2026 06:12PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 155 of 501
Issue #336 -
Peter learns of Nathan’s plan to take care of May after he’s gone.

Then at a yacht christening, Vulture attempts to kill Raymond Trask for Kingpin.

There’s been quite a few cameos these last few issues!

Anyway, Chance (a mercenary) shows up just to leave as quickly after Spidey webs his helmet.

The end sees Doc Ock helping Vulture and heart-breakingly, May says goodbye to Nathan.
Jan 26, 2026 09:58PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 132 of 501
Issue #335 -
Doc Ock continues his recruiting, with Hobgoblin and Mysterio!

Meanwhile, Peter feels a bit sore and (once again) loses his belief that he’s any good.

I kind of get it, I need validation too but this seems like a constant issue for Pete.
He does get it after he beats the Shocker, with science!
A bittersweet moment between May and Nathan.

Later, Peter learns something’s brewing…
Jan 26, 2026 07:13PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 109 of 501
Issue #334 -
A new suited Doc Ock entices Electro to join him!

We learn uni students are more impressed by Iron Man and MJ’s director gets a light dropped on him for losing his cool!

Completely moving on, May wants Peter to follow Nathan. Once again, the old man gets caught up in some trouble.

Meanwhile, Ock threatens Sandman to join his new Sinister Six!

Not sure I read the original team so I'm excited.
Jan 26, 2026 06:32PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 86 of 501
Charles Vess wrote a little essay about how and why he wrote a Spider-Man story in the Highlands of Scotland.

It was cool seeing the real photos with the drawings next to each other.

There’s also a two-page line art with Spidey looking over a small little town. The details were very well done.
Jan 21, 2026 06:48PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


Sophia
Sophia is on page 77 of 501
Spirits of the Earth -
I didn’t know anything about this story and if I had more time and/or patience, I’m sure it would have been more enjoyable.

I really liked the art though. The backgrounds were my favourite.

Peter and MJ go to Scotland and wind up in a mix between fantasy and sci-fi.
Jan 21, 2026 06:17PM
Amazing Spider-Man Epic Collection, Vol. 21: Return of the Sinister Six


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