Uvrón’s Reviews > Biology and Human Behavior: The Neurological Origins of Individuality, 2nd Edition > Status Update
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Disappointing to hear Sapolsky call dopamine and serotonin imbalance 'the two leading theories of depression'. Metastudies don't find any evidence for these hypotheses, and it's frustrating how many experts continue to repeat the claim.
— Apr 15, 2026 09:00AM
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Apr 15, 2026 12:58PM
Were the metastudies also clear when he was writing the book? (2011-12 ish)
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Fair question, I’m not certain. But it’s a very old hypothesis and I’m generally unimpressed with how long it was uncritically repeated without nuance.
His 800-page tome Behave is a IMHO page-turner from beginning to end. I recall estimating he was completely wrong about 3% of the time, but had more than enough juiciness to offer to make up for it. But have also been less impressed by some of his other writings. Maybe I grew a bit since I took up reading again, and Behave was among my first.