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Approximately 97 percent of human genes have homologues in the mouse genome, for example—a clear advantage versus other laboratory organisms. But the nucleotide sequences of mouse and human genomes are only about 50 percent identical.
“more and more artificial mouse models and tissue culture cell lines for cancer drug development. These resources can and should be invested in better pursuits.”
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
“But from my perspective, even if the models worked as well as we had hoped they would, the fundamental problem would still remain—very few effective anticancer treatments exist, so the predictions made through these models are more likely to be useful in what to avoid rather than what to give the patient. I cannot stress this enough times; scientists need to stop making”
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
“We are such stuff as dreams are made on, and our little life is rounded with a sleep.”
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
“Humans do not benefit but are harmed by misleading animal testing, especially when it comes to predicting the efficacy of targeted therapies.”
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
“my own medical perspective is that animal cancer research should be regarded as the scientific equivalent of gossip—with about the same chance of turning out to be true, i.e. truly effective in humans. Some gossip turns out to be true, but most of it does not… and gossip can cause great anguish for those affected, in this case millions of desperate cancer patients worldwide.” He was right.”
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
― The First Cell: And the Human Costs of Pursuing Cancer to the Last
Guy Stark’s 2025 Year in Books
Take a look at Guy Stark’s Year in Books, including some fun facts about their reading.
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